{"id":"W2085644094","doi":"10.1016/j.ab.2010.09.033","title":"Identification of RNA–ligand interactions by affinity electrophoresis","year":2010,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; University of Calgary","keywords":"RNA; Ligand (biochemistry); Aminoglycoside; Ribosomal RNA; Chemistry; Gel electrophoresis; Affinity electrophoresis; Escherichia coli; Molecular biology; Binding site; Polyacrylamide gel electrophoresis; Electrophoresis; Biochemistry; Affinity chromatography; Biology; Enzyme; Receptor; Antibiotics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001706562,0.0001215799,0.0001291965,0.00002185621,0.00005490182,0.00002150369,0.0002176028,0.0001871184,0.0001175348],"category_scores_gemma":[0.0003560637,0.0001187188,0.0001175629,0.00009707809,0.0001101398,0.00000339531,0.00004997614,0.0001496941,0.00001676491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006424138,"about_ca_system_score_gemma":0.00005071677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000090568,"about_ca_topic_score_gemma":0.000004400543,"domain_scores_codex":[0.9991068,0.00001823182,0.0002781561,0.0002962374,0.0001305249,0.000170098],"domain_scores_gemma":[0.9992227,0.00002380645,0.0001179906,0.0004364264,0.0001014393,0.00009764858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003703731,0.00008860323,0.0001262797,0.00001452114,0.00004640654,4.490525e-7,0.000002738532,2.889899e-7,0.9939338,0.0001151668,0.004723622,0.0009111143],"study_design_scores_gemma":[0.00010633,0.00003901225,0.0000730388,0.000004408496,0.00003496785,0.000006683349,0.00001484613,0.00004427472,0.9953245,0.0001891141,0.004034279,0.0001285513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965634,0.0001150624,0.001154079,0.00022598,0.00008473348,0.00006081972,0.00004535706,0.000009548373,0.001740965],"genre_scores_gemma":[0.9971954,0.00005600062,0.0002162866,0.00005336972,0.0001387018,0.00001255392,0.00009961465,0.00001301372,0.002215084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001390722,"threshold_uncertainty_score":0.4841211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005469745139116155,"score_gpt":0.2518815714188333,"score_spread":0.2464118262797172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}