{"id":"W2085667743","doi":"10.1182/asheducation-2006.1.421","title":"The Role of Immunomodulation in the Management of Factor VIII Inhibitors","year":2006,"lang":"en","type":"review","venue":"Hematology","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Rituximab; Immune tolerance; Von Willebrand factor; Immunology; Adverse effect; Clinical trial; Antibody; Immune system; Internal medicine; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002399246,0.0003069894,0.0007444854,0.0004758643,0.0003296593,0.001208688,0.00050173,0.0008023962,0.001271649],"category_scores_gemma":[0.002295542,0.0000876407,0.0004295492,0.0002921968,0.0008698012,0.0009134114,0.0005960799,0.002318583,0.0003755569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005564531,"about_ca_system_score_gemma":0.0008170475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004428008,"about_ca_topic_score_gemma":0.0006626876,"domain_scores_codex":[0.9992775,0.0003669082,0.00006337508,0.00005164464,0.000183296,0.0000572218],"domain_scores_gemma":[0.9984257,0.0009447383,0.000253657,0.00004819265,0.0002058236,0.0001218869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004816283,0.0002434935,0.001995474,0.001824259,0.00007503202,0.0005570764,0.0001772608,0.0006350404,0.00374581,0.00717927,0.005928843,0.9771567],"study_design_scores_gemma":[0.0004876196,0.008729787,0.02759282,0.009143348,0.0006141308,0.009800965,0.0007201515,0.002353902,0.008059262,0.02736615,0.9050138,0.0001180578],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01080628,0.9660207,0.00153036,0.01400318,0.0009985396,0.00003229835,0.00001631612,0.00002674934,0.006565714],"genre_scores_gemma":[0.1763937,0.7991757,0.006165602,0.007912982,0.007670129,0.0000971441,0.00003755844,0.00001915353,0.002528004],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002399246,"threshold_uncertainty_score":0.01268858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04026644151839126,"score_gpt":0.3637879742718271,"score_spread":0.3235215327534359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}