{"id":"W2085714603","doi":"10.1039/c1an15235a","title":"Modified peptide monolayer binding His-tagged biomolecules for small ligand screening with SPR biosensors","year":2011,"lang":"en","type":"article","venue":"The Analyst","topic":"Molecular Junctions and Nanostructures","field":"Engineering","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; PROTEO; Université de Montréal","funders":"","keywords":"Monolayer; Chemistry; Peptide; Surface plasmon resonance; Biomolecule; Biosensor; Ligand (biochemistry); Chelation; Combinatorial chemistry; Biochemistry; Nanotechnology; Receptor; Organic chemistry; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001182687,0.0001788302,0.0001742924,0.0001761616,0.0001823625,0.00004209786,0.000185615,0.0000597445,0.00001670105],"category_scores_gemma":[0.0000100646,0.0001150487,0.0001106959,0.0003029802,0.00003283296,0.00004482647,0.0000197868,0.0001046827,0.000008998722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001603951,"about_ca_system_score_gemma":0.000007395038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000152562,"about_ca_topic_score_gemma":0.0001697543,"domain_scores_codex":[0.9992902,0.00001970322,0.000166061,0.0001726812,0.00009150792,0.0002598119],"domain_scores_gemma":[0.9994994,0.00002842885,0.00004590333,0.0003274672,0.00004079772,0.00005796347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002896552,0.00003656402,0.00147815,0.00009332612,0.001617967,0.00004321111,0.001734531,0.03531573,0.9514114,0.001883007,0.001389339,0.004707155],"study_design_scores_gemma":[0.00117475,0.0001726586,0.00412766,0.00008671795,0.0006365802,0.00004382201,0.0007167554,0.05465591,0.933873,0.0003185236,0.003527902,0.0006657304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8891661,0.00019858,0.1085755,0.0000287091,0.00006666157,0.0001952619,0.00001370044,0.0001363388,0.001619076],"genre_scores_gemma":[0.9901556,0.00001942656,0.009461692,0.00003233714,0.00005590978,0.00002204873,0.00001356558,0.0000469426,0.0001924177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1009895,"threshold_uncertainty_score":0.4691549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02999242624458254,"score_gpt":0.20345585005093,"score_spread":0.1734634238063475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}