{"id":"W2085716329","doi":"10.1002/prp2.72","title":"Bioequivalence of Sandoz methylphenidate osmotic‐controlled release tablet with Concerta<sup>®</sup> (Janssen‐Cilag)","year":2015,"lang":"en","type":"article","venue":"Pharmacology Research & Perspectives","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"inVentiv Health Clinical","funders":"","keywords":"Bioequivalence; Methylphenidate; Confidence interval; Crossover study; Pharmacology; Pharmacokinetics; Bioavailability; Geometric mean; Medicine; Chromatography; Chemistry; Attention deficit hyperactivity disorder; Mathematics; Internal medicine; Statistics; Placebo; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001551405,0.0004487398,0.001143389,0.0003437859,0.0001835954,0.0006576283,0.0005181637,0.0007803504,0.001870982],"category_scores_gemma":[0.001610972,0.0003133555,0.0005791426,0.0002870513,0.000593789,0.0006559332,0.0002560611,0.0005815654,0.000298071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005216234,"about_ca_system_score_gemma":0.000673695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001405355,"about_ca_topic_score_gemma":0.001373428,"domain_scores_codex":[0.9983311,0.0007562201,0.0002020359,0.0002523499,0.0003791335,0.00007909296],"domain_scores_gemma":[0.9994561,0.0001210924,0.0002130274,0.00007273519,0.00005406541,0.00008289479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2956229,0.007189048,0.004166794,0.001101481,0.001047445,0.0000915878,0.0003048166,0.001166605,0.6032481,0.0005863713,0.0004867623,0.08498816],"study_design_scores_gemma":[0.05425934,0.563607,0.09110362,0.0001485867,0.002635611,0.0007033758,0.0004064213,0.01076545,0.2674448,0.0004493537,0.008230519,0.0002458892],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967701,0.00137315,0.0006937548,0.00004059633,0.00003890385,0.0003026587,0.0002739177,0.00002581346,0.0004811469],"genre_scores_gemma":[0.9962828,0.0007295507,0.001686358,0.00005528799,0.0000400979,0.0002686223,0.0003532174,0.00001149675,0.0005725774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001870982,"threshold_uncertainty_score":0.008204699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1641063888695401,"score_gpt":0.4658998360646476,"score_spread":0.3017934471951075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}