{"id":"W2085755215","doi":"10.1007/s00415-012-6727-8","title":"Potassium channels: a review of broadening therapeutic possibilities for neurological diseases","year":2012,"lang":"en","type":"review","venue":"Journal of Neurology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Valeant Pharmaceuticals International; Eisai; Sanofi; GlaxoSmithKline","keywords":"Potassium channel; Neuroscience; Neurology; Pathophysiology; Inward-rectifier potassium ion channel; Potassium; Migraine; Medicine; Voltage-dependent calcium channel; Epilepsy; Biology; Ion channel; Calcium; Chemistry; Endocrinology; Internal medicine; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004187099,0.0002658279,0.001224726,0.0001389827,0.00004251301,0.000008233132,0.0002660224,0.0003823284,0.00004335678],"category_scores_gemma":[0.0003281946,0.000184093,0.0009967668,0.00009386002,0.0001034391,0.000006944674,0.00006692496,0.0002802422,0.000001739315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006084914,"about_ca_system_score_gemma":0.0001654042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":2.003061e-7,"about_ca_topic_score_gemma":9.543872e-8,"domain_scores_codex":[0.9979279,0.0004631744,0.0009735999,0.0002322418,0.0001574678,0.0002456337],"domain_scores_gemma":[0.997873,0.0001332973,0.001375094,0.0002314462,0.0002815489,0.0001056022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008780058,0.0003954906,0.00006275793,0.08051174,0.0006105544,0.00001970181,0.00003081335,0.00002225459,0.0001373727,0.0001482688,0.007611134,0.9095719],"study_design_scores_gemma":[0.0002584624,0.002181871,0.00002157942,0.00203739,0.0009964881,0.0008622608,0.000002572827,0.000009429156,0.000007776342,0.00007089657,0.9934098,0.0001415398],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001148882,0.9962339,0.0005707889,0.0003902799,0.002215781,0.0004137769,0.00003730109,0.000004153119,0.00001915432],"genre_scores_gemma":[0.0005406785,0.995598,0.00004041371,0.001153879,0.002382619,0.00002974215,0.00008192757,0.00003649256,0.0001362237],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9857986,"threshold_uncertainty_score":0.7507094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07026615343910603,"score_gpt":0.3390203330217559,"score_spread":0.2687541795826499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}