{"id":"W2085831929","doi":"10.4061/2011/284728","title":"Genetics and Genomics of Late‐Onset Alzheimer′s Disease and Its Endophenotypes","year":2011,"lang":"en","type":"article","venue":"International Journal of Alzheimer s Disease","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute on Aging; Medical Research Council; Wellcome Trust","keywords":"Endophenotype; Genomics; Genetics; Disease; Biology; Psychology; Medicine; Neuroscience; Genome; Cognition; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001073349,0.0003481363,0.0005103535,0.001050256,0.0001872428,0.001162536,0.0002507162,0.0009555284,0.002190126],"category_scores_gemma":[0.002194355,0.0001652338,0.0004550875,0.0009578874,0.0004421422,0.0006903197,0.0005016972,0.0008012769,0.0003956642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003465905,"about_ca_system_score_gemma":0.0002790225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006587222,"about_ca_topic_score_gemma":0.000702791,"domain_scores_codex":[0.9994622,0.0002172326,0.00005071475,0.0001199312,0.0001017492,0.00004817422],"domain_scores_gemma":[0.9986481,0.0007841015,0.0002376463,0.0000589123,0.0001505672,0.0001207316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001485037,0.0001407242,0.1085986,0.004029108,0.001729599,0.004817483,0.001889438,0.0012848,0.03057154,0.03901321,0.2336611,0.5727794],"study_design_scores_gemma":[0.000157325,0.0004595104,0.5361328,0.001677561,0.001193743,0.01123019,0.000964274,0.0008077752,0.003062354,0.06613528,0.3780525,0.0001266773],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2213431,0.6127849,0.008973562,0.1124001,0.0214912,0.0000894117,0.003719423,0.0002071144,0.01899131],"genre_scores_gemma":[0.3970599,0.4990042,0.008262988,0.02794045,0.05031206,0.000208642,0.003208398,0.0002349895,0.0137684],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002190126,"threshold_uncertainty_score":0.007326663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02953592130347041,"score_gpt":0.2820458911675527,"score_spread":0.2525099698640823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}