{"id":"W2085953508","doi":"10.1016/j.bbrc.2014.08.134","title":"Sonic Hedgehog promotes the survival of neural crest cells by limiting apoptosis induced by the dependence receptor CDON during branchial arch development","year":2014,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Université de Lyon; European Research Council; Institut National Du Cancer; CNIB; Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Agence Nationale de la Recherche","keywords":"Neural crest; Sonic hedgehog; Biology; Cell biology; Neural tube; Morphogen; Endoderm; Internal medicine; Embryonic stem cell; Signal transduction; Embryo; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001198707,0.0001564432,0.0001858788,0.0002285564,0.000220975,0.0004750637,0.000177819,0.0001636008,0.0008726444],"category_scores_gemma":[0.0001304144,0.0001618267,0.0001469274,0.0001132298,0.0002597628,0.0002710215,0.0002610427,0.0005667706,0.0002809691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005102569,"about_ca_system_score_gemma":0.0003636455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001439441,"about_ca_topic_score_gemma":0.003876494,"domain_scores_codex":[0.9998733,0.00001740477,0.000008874666,0.00001377791,0.00003254773,0.00005417677],"domain_scores_gemma":[0.9998975,0.00001916632,0.00002201927,0.000009660695,0.00001627938,0.00003526222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001656052,0.00000636464,0.00043074,0.00001498641,0.000002342924,0.00006401417,0.00002388039,0.00002355929,0.998014,0.0002292429,0.000021955,0.001003212],"study_design_scores_gemma":[0.00001044574,0.0001163667,0.01192045,0.000005067147,0.0000127116,0.0001376757,0.00008562856,0.0003629915,0.9856146,0.00006992599,0.001661606,0.000002550681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963206,0.001369484,0.0007559779,0.00004682413,0.000009958581,0.000004104599,0.00005516264,0.0000166026,0.001421359],"genre_scores_gemma":[0.9949625,0.000587915,0.0005229053,0.00001862775,0.000006169539,0.000007146798,0.0001270638,0.00001057797,0.00375721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001439441,"threshold_uncertainty_score":0.003702223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06383605432923947,"score_gpt":0.3246967964827664,"score_spread":0.2608607421535269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}