{"id":"W2086065790","doi":"10.1021/es5003023","title":"Mechanisms of Toxicity of Hydroxylated Polybrominated Diphenyl Ethers (HO-PBDEs) Determined by Toxicogenomic Analysis with a Live Cell Array Coupled with Mutagenesis in <i>Escherichia coli</i>","year":2014,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Microbial bioremediation and biosurfactants","field":"Environmental Science","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Purdue University","keywords":"Polybrominated diphenyl ethers; Chemistry; Toxicity; Escherichia coli; Toxicogenomics; Mutagenesis; Cytotoxicity; Environmental chemistry; Diphenyl ether; Stereochemistry; Operon; Gene; Biochemistry; Mutation; Gene expression; In vitro; Pollutant; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001466093,0.0003143343,0.000261429,0.0001679901,0.00008736185,0.0002418931,0.0001571299,0.0002719554,0.0004488033],"category_scores_gemma":[0.00009042144,0.0001484988,0.0002651807,0.0001550189,0.0002214517,0.0001993353,0.0001800102,0.0002773437,0.0001862057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002186374,"about_ca_system_score_gemma":0.0001440675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000671392,"about_ca_topic_score_gemma":0.0008157483,"domain_scores_codex":[0.9998587,0.0000203587,0.00001315497,0.00003852442,0.00004162343,0.00002770645],"domain_scores_gemma":[0.9999298,0.00001232479,0.00002841609,0.000006260655,0.00001536201,0.000007874653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003494204,0.000004791763,0.000362901,0.00001874837,0.000002596332,0.00001203839,0.000007480434,0.00005016954,0.999067,0.00001913724,0.000008292185,0.0004118585],"study_design_scores_gemma":[0.00000220835,0.0001672417,0.009435513,0.000003967104,0.00001144291,0.00005923385,0.00004391378,0.0005604185,0.9890843,0.00003683221,0.0005905432,0.000004424831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927648,0.001047536,0.004189226,0.00006684999,0.00001387556,0.00003085838,0.001111303,0.00005602181,0.0007196153],"genre_scores_gemma":[0.9896131,0.001607368,0.004803647,0.0001008218,0.000006514239,0.00008773741,0.001203796,0.0000180313,0.002559082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000671392,"threshold_uncertainty_score":0.001586378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002178365543211855,"score_gpt":0.1662356890528401,"score_spread":0.1640573235096283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}