{"id":"W2086110001","doi":"10.1016/j.dnarep.2005.10.003","title":"Saccharomyces cerevisiae Ogg1 prevents poly(GT) tract instability in the mitochondrial genome","year":2005,"lang":"en","type":"article","venue":"DNA repair","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke; Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"National Cancer Institute; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Biology; Mitochondrial DNA; Mitochondrion; Saccharomyces cerevisiae; DNA repair; AP endonuclease; Genome instability; DNA glycosylase; AP site; DNA damage; DNA-(apurinic or apyrimidinic site) lyase; Base excision repair; Mutant; Molecular biology; Biochemistry; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005556883,0.000244078,0.0002214289,0.00005229776,0.0000828668,0.00003488984,0.0005124571,0.0002173643,0.0001204905],"category_scores_gemma":[0.0001350236,0.0001915845,0.0002910412,0.0001504961,0.00006491974,0.00001429438,0.0001321179,0.0001812825,0.00005699251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005743116,"about_ca_system_score_gemma":0.00009004647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003475726,"about_ca_topic_score_gemma":0.0001433151,"domain_scores_codex":[0.9980236,0.0002856592,0.0004115513,0.0006015348,0.0002767921,0.0004009002],"domain_scores_gemma":[0.998794,0.00002831025,0.0001127023,0.0009477893,0.0000344093,0.00008284628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001416696,0.0008207264,0.00369088,0.00004618599,0.0000709443,0.00002079547,0.0005715332,0.00002507046,0.9735622,0.0001187209,0.00142922,0.01950204],"study_design_scores_gemma":[0.002308474,0.0008130476,0.05131732,0.0000385012,0.00006386761,0.0001173699,0.000389697,0.0002367862,0.2369757,0.00039048,0.7065319,0.0008168031],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949398,0.00152488,0.0001539699,0.0004704959,0.0002121241,0.0006405495,0.0000319824,0.00007540207,0.001950812],"genre_scores_gemma":[0.9954165,0.00008686995,0.00243784,0.0006368703,0.0006920697,0.00009455665,0.00008824538,0.00003032826,0.0005167638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7365865,"threshold_uncertainty_score":0.781259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01027093980994554,"score_gpt":0.2470604679043639,"score_spread":0.2367895280944184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}