{"id":"W2086280521","doi":"10.1182/blood-2009-02-207795","title":"Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McMaster University; Jewish General Hospital","funders":"","keywords":"Antigen presentation; Cross-presentation; Antigen processing; Antigen; Mesenchymal stem cell; Biology; MHC class I; Immune system; Immunology; T cell; CD8; Major histocompatibility complex; Cytotoxic T cell; Antigen-presenting cell; Cell biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003421039,0.0003447417,0.000518254,0.0001384507,0.0004533226,0.00005978422,0.0005632015,0.0003038569,0.0005248807],"category_scores_gemma":[0.00003555427,0.0002757156,0.0002885968,0.0001699435,0.0003003436,0.000192493,0.0001377343,0.0003263212,0.0002876064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001122132,"about_ca_system_score_gemma":0.000168222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001893506,"about_ca_topic_score_gemma":0.000003065716,"domain_scores_codex":[0.9977853,0.000280774,0.0006149158,0.0004104129,0.00009458196,0.0008140295],"domain_scores_gemma":[0.9987839,0.00009357899,0.000272145,0.0006675384,0.000151214,0.00003162832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004750328,0.001498016,0.002965206,0.0000291435,0.0002825603,0.0000214811,0.001613859,0.000009840691,0.9918903,0.00004436244,0.000312837,0.0008573435],"study_design_scores_gemma":[0.002473827,0.000968506,0.007616898,0.00005023724,0.00004760407,0.0001190253,0.0004616264,0.000002613363,0.9704055,0.00004504318,0.01750075,0.0003083826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740717,0.02086878,0.000006856522,0.0000691792,0.0007448002,0.0003963094,0.0000250659,0.0001030184,0.003714256],"genre_scores_gemma":[0.9902392,0.0007380086,0.0000528877,0.00007538286,0.00008645551,0.00001048909,0.00002608927,0.00003135936,0.008740099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02148483,"threshold_uncertainty_score":0.9999695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01864006431971501,"score_gpt":0.2361831983354037,"score_spread":0.2175431340156887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}