{"id":"W2086280521","doi":"10.1182/blood-2009-02-207795","title":"Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McMaster University; Jewish General Hospital","funders":"","keywords":"Antigen presentation; Cross-presentation; Antigen processing; Antigen; Mesenchymal stem cell; Biology; MHC class I; Immune system; Immunology; T cell; CD8; Major histocompatibility complex; Cytotoxic T cell; Antigen-presenting cell; Cell biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000136573,0.0005447408,0.0002989814,0.000166384,0.0001029005,0.0003475379,0.0001261256,0.0003069487,0.001142466],"category_scores_gemma":[0.0001186055,0.00008640303,0.000252326,0.0001896825,0.0001760059,0.0001848443,0.0002289974,0.0005252528,0.0005942672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001318512,"about_ca_system_score_gemma":0.0001233293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001132706,"about_ca_topic_score_gemma":0.0002246773,"domain_scores_codex":[0.9998168,0.00003370806,0.00001965177,0.00002990364,0.00007775782,0.0000221592],"domain_scores_gemma":[0.9998392,0.00003767382,0.0000479331,0.00002142683,0.00002795391,0.0000257247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003733525,0.00001743899,0.0002806731,0.0001040878,0.000009888431,0.00009242776,0.00001855215,0.00008664445,0.9937333,0.0001822026,0.00003838109,0.00539913],"study_design_scores_gemma":[0.000007128851,0.0002495225,0.001695158,0.00001059394,0.00004090459,0.0006619508,0.00003125089,0.0004200967,0.9902232,0.0001066893,0.006549639,0.000003834824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9276763,0.01850271,0.04583498,0.000426779,0.0002622608,0.0001765617,0.0005651044,0.0003135109,0.006241784],"genre_scores_gemma":[0.9867849,0.003749908,0.006851293,0.0001237452,0.00005252412,0.00004469464,0.0002807594,0.00002395546,0.002088205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001142466,"threshold_uncertainty_score":0.003821969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01864006431971501,"score_gpt":0.2361831983354037,"score_spread":0.2175431340156887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}