{"id":"W2086282835","doi":"10.1038/cr.2011.73","title":"Caveolar vesicles generate DNA damage and perpetuate cellular aging","year":2011,"lang":"en","type":"article","venue":"Cell Research","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University","funders":"","keywords":"Biology; DNA damage; Vesicle; DNA; Cell biology; Computational biology; Genetics; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005844454,0.0004150233,0.0003227733,0.0006842265,0.0003491519,0.0006347449,0.0003500446,0.0008496839,0.0008732096],"category_scores_gemma":[0.0003257223,0.0002149664,0.0003848203,0.0002752909,0.0004909302,0.0008927466,0.0006461051,0.0007466463,0.0001985685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005037411,"about_ca_system_score_gemma":0.000295575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006235568,"about_ca_topic_score_gemma":0.000889509,"domain_scores_codex":[0.9998443,0.00002585317,0.00001157184,0.00003089022,0.00004330273,0.00004414539],"domain_scores_gemma":[0.9997888,0.0000316624,0.00005493185,0.00003834612,0.00004447588,0.00004181713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005630989,0.00006150148,0.002878316,0.0001336327,0.00008632368,0.000643736,0.0002487707,0.0001332551,0.9746743,0.009044169,0.0005922264,0.01094065],"study_design_scores_gemma":[0.00008923135,0.0005040223,0.0213242,0.00003523924,0.0001343512,0.00296003,0.0003227048,0.001037695,0.9517346,0.006971962,0.01485445,0.0000315805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9629325,0.02223285,0.008665903,0.001148193,0.000363323,0.0000623641,0.0003305276,0.0002024866,0.004061802],"genre_scores_gemma":[0.9908528,0.003881689,0.001198082,0.000197151,0.00007691559,0.00002285745,0.0001469138,0.0000197861,0.003603817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008732096,"threshold_uncertainty_score":0.003654838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06569629103812386,"score_gpt":0.2973571326755929,"score_spread":0.2316608416374691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}