{"id":"W2086340811","doi":"10.1016/s0168-3659(99)00274-6","title":"Cutaneous vaccination: the skin as an immunologically active tissue and the challenge of antigen delivery","year":2000,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":162,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Medicine; Transdermal; Vaccination; Poliomyelitis; Nasal administration; Immunization; Measles; Immunology; Virology; Immune system; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001571254,0.0005072819,0.002777901,0.0002012374,0.0003494351,0.00003094994,0.0009986914,0.0006556239,0.002141334],"category_scores_gemma":[0.0003438696,0.0002413859,0.0008096907,0.0001864285,0.0005430863,0.0001996578,0.00007925093,0.002663899,0.00003086906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009140171,"about_ca_system_score_gemma":0.000441627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007921849,"about_ca_topic_score_gemma":0.000003355006,"domain_scores_codex":[0.9932073,0.004043759,0.001740722,0.000249106,0.0004046766,0.0003543823],"domain_scores_gemma":[0.9925323,0.004180836,0.002327315,0.0003644883,0.0004191218,0.0001759924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01528815,0.0004452003,3.972853e-7,0.0004796554,0.003011278,0.000459825,0.0006201215,0.0002033637,0.000005193334,0.0005168474,0.000107562,0.9788624],"study_design_scores_gemma":[0.01760042,0.001002671,0.000003377238,0.0006839705,0.005314008,0.002035547,0.0001931433,0.0001764319,0.00002680067,0.001197639,0.9714823,0.000283621],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001193185,0.9922212,0.00005031569,0.0009077391,0.0006344264,0.002073822,0.00004874627,0.00001191237,0.002858652],"genre_scores_gemma":[0.02686933,0.9715501,0.00002925223,0.0004670627,0.0005114375,0.0000612984,0.000008376236,0.00003862852,0.0004644967],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9785788,"threshold_uncertainty_score":0.999637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05962113077968913,"score_gpt":0.4284453961839872,"score_spread":0.3688242654042981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}