{"id":"W2086474341","doi":"10.1210/jc.2004-1636","title":"Extracellular Signal-Regulated Protein Kinase, But Not c-Jun N-Terminal Kinase, Is Activated by Type II Gonadotropin-Releasing Hormone Involved in the Inhibition of Ovarian Cancer Cell Proliferation","year":2005,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"University of British Columbia","keywords":"MAPK/ERK pathway; Kinase; p38 mitogen-activated protein kinases; Cell growth; Protein kinase A; Cancer research; Signal transduction; Mitogen-activated protein kinase; Mitogen-activated protein kinase kinase; Chemistry; Ovarian cancer; Endocrinology; Cell biology; Internal medicine; Molecular biology; Biology; Cancer; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001040279,0.0002666784,0.000578577,0.00007241474,0.0001577204,0.00002121964,0.0005114626,0.0003445919,0.00007025357],"category_scores_gemma":[0.0002682853,0.0001699391,0.0002182794,0.0002359422,0.0003708848,0.00004001787,0.0001070732,0.000800611,0.000002474332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003021929,"about_ca_system_score_gemma":0.0003901666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001155562,"about_ca_topic_score_gemma":0.00002078041,"domain_scores_codex":[0.9964142,0.001052801,0.001488262,0.0002822699,0.0003717888,0.000390663],"domain_scores_gemma":[0.9977536,0.000108155,0.001209902,0.0003771701,0.0004685251,0.00008265179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001982631,0.000431714,0.0001205308,0.00002519998,0.00009936166,0.00002156653,0.000198337,0.0001222581,0.9875085,0.0000790148,0.0009583775,0.008452496],"study_design_scores_gemma":[0.002752825,0.0007605905,0.002417945,0.00005455729,0.0001961793,0.0000865586,0.0001628317,0.0001156648,0.972347,0.0001090351,0.02081615,0.0001806351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703879,0.0263782,0.0003667531,0.002225576,0.000157851,0.0003966412,0.0000143456,0.000005962864,0.00006681456],"genre_scores_gemma":[0.9899365,0.007473595,0.0004413023,0.0007353501,0.0009124635,0.00001685783,0.00003042257,0.00002757168,0.0004259058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01985777,"threshold_uncertainty_score":0.6929914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02257596296009353,"score_gpt":0.3019040475022622,"score_spread":0.2793280845421687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}