{"id":"W2086474341","doi":"10.1210/jc.2004-1636","title":"Extracellular Signal-Regulated Protein Kinase, But Not c-Jun N-Terminal Kinase, Is Activated by Type II Gonadotropin-Releasing Hormone Involved in the Inhibition of Ovarian Cancer Cell Proliferation","year":2005,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"University of British Columbia","keywords":"MAPK/ERK pathway; Kinase; p38 mitogen-activated protein kinases; Cell growth; Protein kinase A; Cancer research; Signal transduction; Mitogen-activated protein kinase; Mitogen-activated protein kinase kinase; Chemistry; Ovarian cancer; Endocrinology; Cell biology; Internal medicine; Molecular biology; Biology; Cancer; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000873786,0.0004562559,0.0002560133,0.0001544149,0.0001635375,0.00019974,0.0001169311,0.0001982647,0.00114702],"category_scores_gemma":[0.00009079729,0.000118056,0.0003812857,0.0001486161,0.0001468608,0.0001169271,0.000121464,0.000449754,0.000257441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001600234,"about_ca_system_score_gemma":0.0002808116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002374681,"about_ca_topic_score_gemma":0.0004643784,"domain_scores_codex":[0.9999144,0.00001134766,0.00001108953,0.00001592992,0.00002046552,0.00002670465],"domain_scores_gemma":[0.9999559,0.000004697148,0.00001724729,0.000002977136,0.000005499237,0.00001371464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004679793,0.00006757768,0.0003660376,0.0002444265,0.00001285315,0.0002059619,0.00001484731,0.00005282379,0.9958822,0.00008813396,0.0001221913,0.002474952],"study_design_scores_gemma":[0.0001785036,0.0008988972,0.04181246,0.00003355884,0.00006680785,0.002417724,0.00009565896,0.00249283,0.9428359,0.0002151202,0.008939325,0.00001334947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832965,0.01099149,0.001928866,0.0002162469,0.0001530106,0.00005493648,0.0004520394,0.00006316171,0.002843808],"genre_scores_gemma":[0.9877467,0.006719762,0.001406487,0.0001243713,0.00003983674,0.0000784858,0.0009041288,0.000008315134,0.00297202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00114702,"threshold_uncertainty_score":0.003837228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02257596296009353,"score_gpt":0.3019040475022622,"score_spread":0.2793280845421687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}