{"id":"W2086479089","doi":"10.1186/1471-2369-14-25","title":"The rationale and design of Insight into Nephrotic Syndrome: Investigating Genes, Health and Therapeutics (INSIGHT): a prospective cohort study of childhood nephrotic syndrome","year":2013,"lang":"en","type":"article","venue":"BMC Nephrology","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Saskatchewan; Institute for Clinical Evaluative Sciences; University Health Network; University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Hospital for Sick Children","keywords":"Nephrotic syndrome; Medicine; Kidney disease; Cohort study; Cohort; Nephrology; Internal medicine; Prospective cohort study; Disease; Focal segmental glomerulosclerosis; Pediatrics; Minimal change disease; Longitudinal study; Proteinuria; Pathology; Kidney","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003879016,0.0002538268,0.0007418303,0.0001555465,0.0002805433,0.0000315222,0.0001099755,0.0001010417,0.00001632684],"category_scores_gemma":[0.0001568734,0.0001715631,0.00005505135,0.0003288414,0.0006396509,0.0001285559,0.000113,0.0002012303,0.000003889239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004484705,"about_ca_system_score_gemma":0.0004795083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004146262,"about_ca_topic_score_gemma":0.0001107992,"domain_scores_codex":[0.9977981,0.0004909011,0.0006746122,0.0004005878,0.0003272337,0.0003085757],"domain_scores_gemma":[0.9982312,0.0005505342,0.0003818947,0.0003828091,0.0002209299,0.0002325742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002819576,0.001054479,0.9753526,0.0006797944,0.0009901299,0.00003432697,0.01429419,0.0001244001,0.00389583,0.0008133885,0.00007871346,0.002400192],"study_design_scores_gemma":[0.002106372,0.004803784,0.9864095,0.00009935074,0.0002743163,0.0007149841,0.001902549,0.001122356,0.0000510897,0.002287868,0.00008502814,0.0001427984],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756888,0.01747785,0.0003014334,0.0006301738,0.00004402774,0.005809772,0.000003735118,0.00002564093,0.00001853969],"genre_scores_gemma":[0.9951557,0.001190628,0.002073672,0.00102254,0.00002846177,0.0004623485,0.000008614624,0.00003002314,0.00002803165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01946685,"threshold_uncertainty_score":0.699614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02062223923232501,"score_gpt":0.2586332186078995,"score_spread":0.2380109793755744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}