{"id":"W2086506167","doi":"10.1038/cdd.2009.106","title":"PICK1-mediated GluR2 endocytosis contributes to cellular injury after neuronal trauma","year":2009,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Ontario Neurotrauma Foundation; Heart and Stroke Foundation of Canada","keywords":"AMPA receptor; Excitotoxicity; Cell biology; Glutamate receptor; Internalization; NMDA receptor; Neuroscience; Biology; Programmed cell death; Chemistry; Receptor; Biochemistry; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003980797,0.0007565601,0.0008510193,0.000856213,0.0008258648,0.00105732,0.0005390106,0.001117425,0.001818856],"category_scores_gemma":[0.0004879634,0.0003456739,0.0008640313,0.0004214289,0.0006136268,0.001249073,0.001033398,0.001336094,0.0007598143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001286723,"about_ca_system_score_gemma":0.0004795879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001323756,"about_ca_topic_score_gemma":0.001088852,"domain_scores_codex":[0.9995354,0.00004553377,0.00004525411,0.00004586185,0.0001282829,0.0001995283],"domain_scores_gemma":[0.9997156,0.00001776898,0.00008416104,0.0000438288,0.00006007512,0.00007851857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002571929,0.00009826928,0.002211315,0.0003282714,0.00009370662,0.002540611,0.0001608047,0.0007339432,0.9793866,0.001888714,0.0005825647,0.009403222],"study_design_scores_gemma":[0.00007026903,0.0004977029,0.05994275,0.00007002692,0.0002290869,0.01173444,0.0007600413,0.003951876,0.9148534,0.002582799,0.005242729,0.0000649391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863091,0.005905599,0.004292074,0.0004633223,0.00009096316,0.00003806119,0.0002335654,0.0001056897,0.002561522],"genre_scores_gemma":[0.9939662,0.002086594,0.0009778395,0.00007563699,0.00004185513,0.00003029933,0.0001892042,0.00002961033,0.002602833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001818856,"threshold_uncertainty_score":0.009335816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02376619291081269,"score_gpt":0.2809931050406733,"score_spread":0.2572269121298607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}