{"id":"W2086563378","doi":"10.1016/j.jchromb.2010.03.018","title":"Development and validation of a sensitive HPLC method for the quantification of HI-6 in guinea pig plasma and evaluated in domestic swine","year":2010,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Defence Research and Development Canada","funders":"","keywords":"Chemistry; Chromatography; Pharmacokinetics; High-performance liquid chromatography; Detection limit; Intravenous bolus; Guinea pig; Pharmacology; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001769714,0.0005632806,0.0004483327,0.0006234423,0.0004042895,0.0005498166,0.0006121709,0.0009890848,0.0005180316],"category_scores_gemma":[0.0009840393,0.0004715633,0.0004888076,0.0002718001,0.0007129163,0.0003893249,0.0002895465,0.0009301752,0.0005218417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000460112,"about_ca_system_score_gemma":0.00091538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002296969,"about_ca_topic_score_gemma":0.002956746,"domain_scores_codex":[0.998882,0.0003498213,0.00005296357,0.0002142187,0.0004410658,0.00005988586],"domain_scores_gemma":[0.9993031,0.00015893,0.0001323307,0.00007371954,0.0002613851,0.0000705175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002926411,0.0001552279,0.001774833,0.00009473143,0.00004514186,0.00005489671,0.00005076181,0.0002431423,0.9847975,0.0000910318,0.00008455451,0.01231533],"study_design_scores_gemma":[0.00006635636,0.003605471,0.01012318,0.00003331113,0.0001659183,0.0006702029,0.00006975055,0.003217686,0.9784583,0.0001005808,0.003456428,0.00003277931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7452628,0.005449591,0.2438459,0.0004657472,0.000351962,0.0007881337,0.0008573177,0.0006602727,0.002318278],"genre_scores_gemma":[0.7958954,0.002897564,0.194497,0.0007093953,0.0001319369,0.0005167654,0.001064767,0.00008467551,0.004202389],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.002296969,"threshold_uncertainty_score":0.0093593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02741424213035922,"score_gpt":0.3535968486975926,"score_spread":0.3261826065672334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}