{"id":"W2086599623","doi":"10.7554/elife.00824","title":"Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa","year":2013,"lang":"en","type":"article","venue":"eLife","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Foundation Fighting Blindness; Grousbeck Family Foundation; National Eye Institute; Howard Hughes Medical Institute","keywords":"Retinitis pigmentosa; Cell biology; Developmental biology; Biology; Chemistry; Neuroscience; Retina","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007488549,0.0002228477,0.0001542641,0.00005225791,0.0000893473,0.00007279339,0.0001967987,0.0001222867,0.0008752004],"category_scores_gemma":[0.00008264434,0.0002140597,0.00008063712,0.0001193654,0.00007506688,0.000007976094,0.0001399282,0.00007680811,0.00219738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001702445,"about_ca_system_score_gemma":0.00007462687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005211533,"about_ca_topic_score_gemma":0.00001203333,"domain_scores_codex":[0.9985968,0.00006152479,0.0002646807,0.0004442944,0.0002614363,0.0003712572],"domain_scores_gemma":[0.9991656,0.000009979427,0.00007870209,0.0002969453,0.0001356323,0.0003131407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005479132,0.00004293396,0.0007689926,0.000007701383,0.00002515484,0.000001808248,0.0005175167,0.00000563367,0.8287587,0.00001567889,0.1665617,0.003239384],"study_design_scores_gemma":[0.000288197,0.0002888678,0.001136286,0.00001782574,0.000003740336,0.000001797418,0.0002385628,0.000004567938,0.6468625,0.00003216642,0.3508847,0.0002407286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868838,0.000298963,0.000111192,0.0005715266,0.0003702516,0.0006542961,0.00001464049,0.00003258259,0.0110627],"genre_scores_gemma":[0.9868207,0.0005689078,0.004357952,0.003877372,0.000186442,0.0002881376,0.0002066675,0.00005072145,0.003643081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1843231,"threshold_uncertainty_score":0.9985795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007371899984666156,"score_gpt":0.2067706739190331,"score_spread":0.1993987739343669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}