{"id":"W2086606630","doi":"10.1038/nrc2127","title":"Insights from transgenic mouse models of ERBB2-induced breast cancer","year":2007,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":268,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Genetically modified mouse; Breast cancer; Transgene; Biology; Cancer research; Cancer; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002450042,0.0008699117,0.002677122,0.0001404414,0.00006597047,0.00002081767,0.0007908564,0.002499227,0.0002666469],"category_scores_gemma":[0.00003085697,0.0006393871,0.001419172,0.0004210055,0.00007552184,0.00001046971,0.0001186081,0.00135021,0.00002526513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001330024,"about_ca_system_score_gemma":0.0008259558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002469388,"about_ca_topic_score_gemma":0.00041814,"domain_scores_codex":[0.9966606,0.0003278416,0.001172069,0.001026414,0.0003644084,0.0004486797],"domain_scores_gemma":[0.9976064,0.00003759354,0.0008771681,0.001037816,0.0002257105,0.0002153019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003459425,0.00005660051,9.593618e-7,0.01257603,0.0004677531,0.000002062839,0.00003163033,0.000002350826,0.005820284,0.0000735171,0.001763758,0.9791704],"study_design_scores_gemma":[0.0002827595,0.00004237919,0.000001419532,0.01370372,0.0009278335,0.000006946706,0.00000227593,0.000001744119,0.009956609,0.00004207881,0.9743424,0.000689815],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002643799,0.9936067,0.00007638571,0.00002164165,0.0006472114,0.00187301,0.002778891,0.0000207606,0.0007110104],"genre_scores_gemma":[0.0004521325,0.9949971,0.0002065306,0.000388511,0.001700269,0.0007881038,0.0008762654,0.0001504924,0.0004405433],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9784806,"threshold_uncertainty_score":0.9996057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06266908915454059,"score_gpt":0.3627754773955944,"score_spread":0.3001063882410538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}