{"id":"W2086674946","doi":"10.1523/jneurosci.3791-07.2008","title":"Neurogenic Role of the Depolarizing Chloride Gradient Revealed by Global Overexpression of KCC2 from the Onset of Development","year":2008,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Université de Montréal","funders":"National Institutes of Health; McGill University Health Centre; McGill University","keywords":"Neurogenesis; Depolarization; Cotransporter; Zebrafish; Neuroscience; Embryonic stem cell; Biology; Cell biology; Lithium chloride; Glycine; Iron(III) chloride; Chloride; Chemistry; Endocrinology; Biochemistry; Sodium; Gene; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001046094,0.0005358401,0.0002913239,0.0002744712,0.0002023643,0.0003937071,0.0002410371,0.0003564814,0.001080715],"category_scores_gemma":[0.0001550752,0.0002854009,0.0001915114,0.0001088429,0.0005316138,0.0003029523,0.0004139399,0.0007113693,0.0003034406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005174667,"about_ca_system_score_gemma":0.0004416658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001608357,"about_ca_topic_score_gemma":0.002943726,"domain_scores_codex":[0.9998547,0.00001280829,0.00002002461,0.0000443555,0.00003519818,0.00003295089],"domain_scores_gemma":[0.9998199,0.00002359798,0.0000570513,0.00002274392,0.00002040203,0.00005626856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002712013,0.000002546613,0.00007242077,0.00001065662,0.000001249464,0.00003845079,0.000008494826,0.00002578155,0.9996289,0.00004727688,0.000006390083,0.000130613],"study_design_scores_gemma":[0.00000890587,0.00006282838,0.004023832,0.000006066145,0.00001144887,0.0002072661,0.00002927933,0.0003816448,0.9943508,0.00002947607,0.0008831695,0.000005237808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954637,0.0008162236,0.001815521,0.00009107155,0.00002726017,0.00001505041,0.0004142827,0.00007610067,0.001280812],"genre_scores_gemma":[0.9944611,0.000556012,0.002023515,0.00004639506,0.000006818062,0.00003411203,0.0003377852,0.00005522212,0.002479048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001608357,"threshold_uncertainty_score":0.003754556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04624944313926092,"score_gpt":0.3062985847670046,"score_spread":0.2600491416277437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}