{"id":"W2086698425","doi":"10.1016/j.cellsig.2009.03.011","title":"Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK","year":2009,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"","keywords":"Lysophosphatidic acid; G protein-coupled receptor; Receptor; Cell biology; G protein; G protein-coupled receptor kinase; Biology; Endocytosis; HEK 293 cells; GTPase-activating protein; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000480408,0.0002439219,0.0003028206,0.00006713144,0.0001373002,0.00004193249,0.0001528854,0.0002191423,0.00006201196],"category_scores_gemma":[0.0000659212,0.0002518084,0.0001219339,0.0001414611,0.0000758453,0.00001597187,0.00004477096,0.0001283733,0.000004775392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009596932,"about_ca_system_score_gemma":0.00004413506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000811376,"about_ca_topic_score_gemma":4.725466e-7,"domain_scores_codex":[0.9984314,0.00007860978,0.0004481565,0.0004652323,0.0002475193,0.0003291038],"domain_scores_gemma":[0.9992927,0.000021206,0.000217654,0.0002216691,0.0001116516,0.0001351673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009471978,0.00004455329,0.0001565551,0.00002480141,0.00003733928,0.000001500571,0.0001367189,0.0004618625,0.9953696,0.0002717075,0.0003858463,0.003014867],"study_design_scores_gemma":[0.0006866464,0.0002038263,0.0001141595,0.00005274067,0.0000487301,0.000003986095,0.00006806443,0.0009696602,0.9933417,0.0003008734,0.003930717,0.0002789286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9331984,0.01979086,0.04637786,0.00007752878,0.0001682551,0.000177606,0.00001268982,0.00002409261,0.0001727209],"genre_scores_gemma":[0.9948433,0.0005060328,0.003360861,0.0001463545,0.0005333374,0.000004818913,0.0002891081,0.00003045764,0.000285698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06164495,"threshold_uncertainty_score":0.9999934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00640216006518509,"score_gpt":0.203661740179394,"score_spread":0.1972595801142089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}