{"id":"W2086714780","doi":"10.1172/jci59755","title":"The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":763,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; McGill University; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Acetaminophen; DNA fragmentation; Fragmentation (computing); Mitochondrial DNA; Nuclear DNA; Toxicity; Apoptosis; DNA damage; Programmed cell death; Glutamate dehydrogenase; Mitochondrial toxicity; Mitochondrion; Liver injury; Biology; Pharmacology; Internal medicine; Medicine; Glutamate receptor; DNA; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null}