{"id":"W2086717609","doi":"10.1002/cphc.201100728","title":"Electrochemical “Signal‐On” Reporter for Amyloid Aggregates","year":2011,"lang":"en","type":"article","venue":"ChemPhysChem","topic":"Ferrocene Chemistry and Applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Chemistry; Peptide; Redox; Circular dichroism; Electrochemistry; Fibril; Crystallography; Biophysics; Organic chemistry; Biochemistry; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000605452,0.0002736262,0.0002328428,0.00001805797,0.0001148756,0.00002047016,0.0003494432,0.000213935,0.002167164],"category_scores_gemma":[0.00008831496,0.0002693077,0.0002072915,0.0001063972,0.00009285182,0.00006265788,0.00004424976,0.0001951896,0.00008969361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005705597,"about_ca_system_score_gemma":0.00005303795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001793669,"about_ca_topic_score_gemma":1.861679e-7,"domain_scores_codex":[0.9985453,0.000001872809,0.000322831,0.0005491601,0.0001498027,0.000431001],"domain_scores_gemma":[0.9988555,0.0001018837,0.0001637072,0.0006036335,0.0001044072,0.0001708889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001082651,0.0002331308,0.0001687882,0.0001363491,0.00004756617,0.000003269424,0.0001089649,1.155445e-7,0.9932193,0.0004221424,0.004846412,0.0007057294],"study_design_scores_gemma":[0.0004393779,0.00002054948,0.00001482468,0.00003925438,0.00003386417,0.00002429799,0.00005969111,0.00005838126,0.9650979,0.00296034,0.03093124,0.0003202884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7447103,0.00012944,0.0005356073,0.0002001862,0.0000286656,0.0001568524,0.00003897894,0.0003643924,0.2538355],"genre_scores_gemma":[0.9884654,0.00001253909,0.004031792,0.0002510893,0.0004388331,0.0005046162,0.0001776657,0.00005793985,0.006060085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2477755,"threshold_uncertainty_score":0.9999759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02891729581418548,"score_gpt":0.2451792106878248,"score_spread":0.2162619148736393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}