{"id":"W2086739899","doi":"10.1039/c0ob01089h","title":"Multifunctional multivalency: a focused library of polymeric cholera toxin antagonists","year":2011,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Alberta Innovates; Alberta Glycomics Centre; Bill and Melinda Gates Foundation","keywords":"Chemistry; Cholera toxin; Conjugate; Galactose; Toxin; Combinatorial chemistry; Dextran; Stereochemistry; Biochemistry; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009519988,0.0005715186,0.0003084463,0.0003852724,0.000135747,0.0004077021,0.0003432539,0.0002356765,0.001208817],"category_scores_gemma":[0.0001089687,0.000167792,0.0001507493,0.0003148429,0.0001233552,0.0001478992,0.0003196116,0.0004820592,0.0006068263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003700492,"about_ca_system_score_gemma":0.000196757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004069661,"about_ca_topic_score_gemma":0.0007514402,"domain_scores_codex":[0.9998993,0.00001335131,0.000006193703,0.00002611947,0.00002854004,0.00002658114],"domain_scores_gemma":[0.9999521,0.000005464159,0.000009044325,0.000006185706,0.000008361506,0.00001892265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004869672,0.00003751203,0.00009624404,0.00002409681,0.000006215828,0.00004044217,0.000009491574,0.0002108238,0.9936188,0.0001682435,0.00008114235,0.005658273],"study_design_scores_gemma":[0.00003358289,0.0007325625,0.00132466,0.000009857011,0.0000535267,0.0003569867,0.00001460383,0.001059324,0.9859406,0.00005927962,0.01040424,0.00001083934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9717139,0.004822311,0.0142134,0.0002093001,0.00005368575,0.0002045032,0.0006717244,0.0003353028,0.007775908],"genre_scores_gemma":[0.9817629,0.003129218,0.006933597,0.0001809489,0.00002305697,0.000106331,0.0008151489,0.0000650895,0.006983704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001208817,"threshold_uncertainty_score":0.004043877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02208618744632015,"score_gpt":0.2508015313882936,"score_spread":0.2287153439419734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}