{"id":"W2086775915","doi":"10.1007/s10549-008-0060-z","title":"A common Greenlandic Inuit BRCA1 RING domain founder mutation","year":2008,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Ovarian cancer; Genetics; Founder effect; Mutation; Biology; Population; Breast cancer; Single-nucleotide polymorphism; Cancer; Haplotype; Medicine; Gene; Genotype","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001067735,0.0008952778,0.0004788903,0.001293406,0.001836411,0.0004376057,0.0007092103,0.001171568,0.00627486],"category_scores_gemma":[0.0006498636,0.0001822891,0.0003937173,0.0009895698,0.0007242903,0.0002717336,0.0005039565,0.0005473384,0.0006706595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007073538,"about_ca_system_score_gemma":0.0008426821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05705329,"about_ca_topic_score_gemma":0.115961,"domain_scores_codex":[0.9998267,0.00001081573,0.00001470018,0.00005789853,0.00004283104,0.00004714453],"domain_scores_gemma":[0.9997372,0.00006017533,0.00006819981,0.00001550869,0.0000409393,0.00007789265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.0002404586,0.0002041556,0.06258589,0.0001118303,0.00006257216,0.8720056,0.002944592,0.0001823346,0.03864277,0.003149191,0.005511717,0.01435888],"study_design_scores_gemma":[0.00003763341,0.000270906,0.1251549,0.00009230916,0.0001354047,0.8442878,0.002262319,0.0006525204,0.007065541,0.001060509,0.01891378,0.00006624002],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9662386,0.0007095997,0.001526301,0.002252091,0.0002498002,0.00010547,0.001937348,0.0001462006,0.02683466],"genre_scores_gemma":[0.9879628,0.0002596801,0.0009994287,0.000829095,0.00004114413,0.00001373224,0.0003332958,0.0000705583,0.00949034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05705329,"threshold_uncertainty_score":0.1134424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04891071369308564,"score_gpt":0.3563522990661232,"score_spread":0.3074415853730376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}