{"id":"W2086801987","doi":"10.1021/bi047383o","title":"A Structural Model for the Osmosensor, Transporter, and Osmoregulator ProP of<i>Escherichia coli</i>","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Periplasmic space; Major facilitator superfamily; Symporter; Escherichia coli; Transporter; Biophysics; Biochemistry; Transmembrane domain; Cytoplasm; Helix (gastropod); Chemistry; Protein structure; ATP-binding cassette transporter; Biology; Membrane transport protein; Lactose permease; C-terminus; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006979537,0.0001586854,0.0001437583,0.000009400073,0.00007065432,0.00001263264,0.0002020853,0.0002837158,0.000007115671],"category_scores_gemma":[0.00001862464,0.0001165554,0.00008588014,0.00004057923,0.0002242738,0.000001685114,0.00005189699,0.0000673571,3.662122e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005822442,"about_ca_system_score_gemma":0.00006823871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001930298,"about_ca_topic_score_gemma":0.000006966984,"domain_scores_codex":[0.9992279,0.000005502028,0.0002048775,0.000293479,0.00006757525,0.0002007005],"domain_scores_gemma":[0.9994479,0.000007305105,0.00008724481,0.0003400409,0.00006618825,0.00005129615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001282569,0.00001781052,0.0001031129,0.00004560139,0.00004413978,1.230581e-7,0.00002200508,0.00007674831,0.9950256,0.00003527365,0.0005860789,0.003915251],"study_design_scores_gemma":[0.0005511416,0.00008185117,0.0004327084,0.000006196447,0.00004141876,0.000008848679,0.00001977107,0.01136764,0.9803968,0.00004587407,0.006886669,0.0001610864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964722,0.001450673,0.0008625883,0.0007291682,0.00005036888,0.0002577532,0.0001290302,0.00001120771,0.00003703085],"genre_scores_gemma":[0.9937269,0.0001548788,0.004891863,0.0002126283,0.0002560136,0.00003381605,0.00006286257,0.00001992381,0.000641133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01462881,"threshold_uncertainty_score":0.475299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009690820266114284,"score_gpt":0.2207539914882281,"score_spread":0.2110631712221138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}