{"id":"W2086808888","doi":"10.1016/j.neurobiolaging.2014.10.018","title":"CaMKII-dependent dendrite ramification and spine generation promote spatial training-induced memory improvement in a rat model of sporadic Alzheimer's disease","year":2014,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Connaught Fund; Alzheimer's Association","keywords":"Long-term potentiation; Neuroscience; Dendritic spine; Dentate gyrus; Synaptic plasticity; Neuroplasticity; Perforant path; Psychology; Hippocampal formation; Postsynaptic potential; Hippocampus; Chemistry; Receptor; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004347078,0.0001691805,0.000321927,0.0003084796,0.00009897054,0.00001312855,0.000267967,0.00005639419,0.000004347509],"category_scores_gemma":[0.0001897167,0.0001588222,0.00004725741,0.0002219725,0.000335197,0.0001578271,0.0001255851,0.0002415537,0.000001601056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001336989,"about_ca_system_score_gemma":0.00010904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001672593,"about_ca_topic_score_gemma":0.000009769931,"domain_scores_codex":[0.9979702,0.0004074359,0.0004399727,0.0006672626,0.0001779518,0.00033714],"domain_scores_gemma":[0.9992568,0.0001050841,0.0002345625,0.0002530843,0.00003365966,0.0001167498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003869755,0.00009514476,0.0002476949,0.00003712122,0.000001802492,0.00001077721,0.0002000087,0.0007944608,0.9806436,0.00009034861,9.999083e-7,0.0178393],"study_design_scores_gemma":[0.0007136572,0.0003779368,0.0007712492,0.00001971143,0.00002828053,0.00001062342,0.000007507938,0.1051933,0.8927161,0.00004657314,0.000008171937,0.0001068805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984205,0.0001819226,0.0002116577,0.0003299903,0.0002511859,0.0005623945,0.000006774293,0.00002316432,0.00001238493],"genre_scores_gemma":[0.9986195,0.0008760138,0.00003568349,0.0003613675,0.00003999309,0.00003550325,0.000002056232,0.00001700461,0.00001289253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1043988,"threshold_uncertainty_score":0.6476582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08490407553965201,"score_gpt":0.3209518315424291,"score_spread":0.2360477560027771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}