{"id":"W2086834071","doi":"10.1016/j.coph.2008.09.004","title":"Proton pump inhibitors: the beginning of the end or the end of the beginning?","year":2008,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Gastroesophageal reflux and treatments","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"GERD; Gastric acid; Medicine; Proton-pump inhibitor; Peptic; Omeprazole; Intensive care medicine; Drug; Pharmacology; Peptic ulcer; Disease; Reflux; Internal medicine; Secretion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004782984,0.0005313289,0.001375132,0.0001628777,0.0002443277,0.000009319366,0.0009698737,0.0002363507,0.0002456534],"category_scores_gemma":[0.0001720282,0.0001696831,0.0007516603,0.000850854,0.001266375,0.00004636851,0.0005141065,0.001528831,0.00001344202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002169099,"about_ca_system_score_gemma":0.001015968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001558016,"about_ca_topic_score_gemma":8.140067e-7,"domain_scores_codex":[0.9963123,0.001024805,0.00113023,0.0004497042,0.000596089,0.000486919],"domain_scores_gemma":[0.9971175,0.0006866085,0.001246459,0.0007537099,0.0001168157,0.00007890676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001725957,0.001560099,0.01204402,0.02472267,0.001185666,0.00003146064,0.001483763,0.000009771751,0.00002025158,0.0001362579,0.02571235,0.9329211],"study_design_scores_gemma":[0.001747413,0.0002320431,0.001176271,0.009126619,0.0008471119,0.0002738323,0.00002906249,0.000009984167,0.0003294477,0.0000222889,0.9861008,0.0001051327],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00167131,0.9750847,0.000002056413,0.001202078,0.01329921,0.008390078,0.00009632998,0.00002060764,0.0002336208],"genre_scores_gemma":[0.01694304,0.9797159,0.00000757081,0.00009516804,0.001317115,0.001597865,0.00005169685,0.00005583531,0.0002158065],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9603884,"threshold_uncertainty_score":0.6919478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1176514645510631,"score_gpt":0.4419279881416924,"score_spread":0.3242765235906293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}