{"id":"W2086850946","doi":"10.1002/prot.22959","title":"Is there nascent structure in the intrinsically disordered region of troponin I?","year":2010,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Wolfson Foundation","keywords":"Troponin C; Biophysics; Troponin I; Actin; Chemistry; Linker; Sarcomere; Protein structure; Myosin; Crystallography; Biochemistry; Myocyte; Biology; Cell biology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009780542,0.0001569353,0.0002672419,0.00009483855,0.00009639794,0.00002546188,0.00006725483,0.0001511899,0.00005059902],"category_scores_gemma":[0.00008099261,0.00008499004,0.00007373148,0.0002332349,0.0001471898,0.0000871814,0.00004105102,0.0004581685,8.402232e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001136423,"about_ca_system_score_gemma":0.0000383535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002198517,"about_ca_topic_score_gemma":0.0001382079,"domain_scores_codex":[0.9991441,0.00002230639,0.0003211233,0.0001077039,0.0002548313,0.0001499191],"domain_scores_gemma":[0.9994269,0.00002438858,0.0001405514,0.0002688114,0.00009673598,0.00004264012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.004387238,0.0004327101,0.2256885,0.004183235,0.000697891,0.00004846054,0.0567316,0.00001197827,0.06414367,0.02513841,0.006907044,0.6116292],"study_design_scores_gemma":[0.006058232,0.001467174,0.9136412,0.0002552419,0.0003647416,0.001010995,0.01077292,0.0009980899,0.008443821,0.006852113,0.04967204,0.0004634357],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947136,0.0002865796,0.001010995,0.001867979,0.0002925178,0.0009299485,0.00003049854,0.00002410529,0.0008437652],"genre_scores_gemma":[0.9967209,0.0001135127,0.002312022,0.0006458125,0.0001336111,0.000009438991,0.0000212694,0.000007278494,0.00003614093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6879527,"threshold_uncertainty_score":0.3465793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008660135100313344,"score_gpt":0.2259899685681426,"score_spread":0.2173298334678292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}