{"id":"W2086850946","doi":"10.1002/prot.22959","title":"Is there nascent structure in the intrinsically disordered region of troponin I?","year":2010,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Wolfson Foundation","keywords":"Troponin C; Biophysics; Troponin I; Actin; Chemistry; Linker; Sarcomere; Protein structure; Myosin; Crystallography; Biochemistry; Myocyte; Biology; Cell biology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004228752,0.0001730192,0.000250991,0.0001332367,0.0002988957,0.0005146202,0.0005318936,0.0007864209,0.0005970175],"category_scores_gemma":[0.001151841,0.0002285391,0.000193472,0.0002110538,0.001106545,0.001570098,0.0002571373,0.0005533142,0.0002591409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003141383,"about_ca_system_score_gemma":0.0002539096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007153319,"about_ca_topic_score_gemma":0.0008125094,"domain_scores_codex":[0.9998885,0.000009482822,0.000006528851,0.00004618173,0.000028916,0.00002024116],"domain_scores_gemma":[0.9992746,0.0002037052,0.0002667849,0.00007912747,0.00008007868,0.00009578562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003972437,0.00009781901,0.02389254,0.000531051,0.0000447376,0.001787173,0.0006743377,0.0008480435,0.9470283,0.00513966,0.0002931688,0.01926594],"study_design_scores_gemma":[0.0001954576,0.003420825,0.2363275,0.0006336091,0.0003615177,0.009085397,0.003293721,0.02437417,0.6568,0.03318315,0.03210587,0.0002187745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983119,0.006485476,0.008044669,0.0008924041,0.00009701206,0.00001379194,0.00009917511,0.0001020281,0.001146457],"genre_scores_gemma":[0.9937571,0.002007031,0.003274927,0.0003087896,0.00006049046,0.000007708519,0.0001852702,0.00002080602,0.0003777324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007864209,"threshold_uncertainty_score":0.002279222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008660135100313344,"score_gpt":0.2259899685681426,"score_spread":0.2173298334678292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}