{"id":"W2086860055","doi":"10.1039/c3dt51152a","title":"A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO)","year":2013,"lang":"en","type":"article","venue":"Dalton Transactions","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministero dell'Università e della Ricerca; Ryerson University","keywords":"Translocator protein; Imidazopyridine; Chemistry; Ligand (biochemistry); Combinatorial chemistry; Biophysics; Biochemistry; Medicine; Biology; Receptor; Internal medicine; Inflammation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00008707947,0.0002482503,0.0002968992,0.00009231496,0.0002174543,0.00003649441,0.000155127,0.0001459196,0.005684871],"category_scores_gemma":[0.00001386794,0.0002349244,0.0002031964,0.0004834436,0.0001045098,0.0001327073,0.000003870235,0.0005162589,0.0008082821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001233925,"about_ca_system_score_gemma":0.0001469735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003467381,"about_ca_topic_score_gemma":0.000001827189,"domain_scores_codex":[0.9983619,0.00002640708,0.0003820596,0.0004490271,0.0003062138,0.0004743682],"domain_scores_gemma":[0.9983646,0.00003085416,0.00002782136,0.0004061425,0.00011101,0.001059547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001549658,0.0007644797,0.00001478782,0.0001725594,0.0001109791,0.000009767487,0.0002480185,0.002260121,0.9848707,0.000269241,0.002751568,0.008372803],"study_design_scores_gemma":[0.00237244,0.0001334192,0.000364127,0.00007147154,0.0003540947,0.00008480769,0.0001036121,0.1252568,0.8158292,0.0002913936,0.05467294,0.0004657263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4362135,0.0002615004,0.5178453,0.03415403,0.0001115095,0.004172692,0.0001783698,0.0005517984,0.00651131],"genre_scores_gemma":[0.9798696,0.00002096621,0.01015807,0.001861003,0.0001082522,0.00195961,0.00004260048,0.00004469398,0.005935225],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5436561,"threshold_uncertainty_score":0.9999697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05701071075540631,"score_gpt":0.3374166845065024,"score_spread":0.280405973751096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}