{"id":"W2086887789","doi":"10.1111/j.1742-7843.2006.00010.x","title":"Vanilloid (Subtype 1) Receptor‐Modulatory Drugs Inhibit [<sup>3</sup>H]Batrachotoxinin‐A 20‐α‐benzoate Binding to Na<sup>+</sup>Channels","year":2006,"lang":"en","type":"article","venue":"Basic & Clinical Pharmacology & Toxicology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Capsazepine; Chemistry; Sodium channel; Batrachotoxin; Veratridine; Capsaicin; Pharmacology; Depolarization; Sodium; Radioligand; Biophysics; Receptor; Allosteric regulation; TRPV1; Stereochemistry; Biochemistry; Transient receptor potential channel; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007305951,0.0002817358,0.0003158482,0.00009233013,0.0001392554,0.0001779985,0.0001784647,0.0001759404,0.001404201],"category_scores_gemma":[0.0001815704,0.0001271235,0.0001870085,0.00009672087,0.0001873419,0.0002098747,0.0001157679,0.0003661299,0.0003345725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000286097,"about_ca_system_score_gemma":0.0001826329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008228096,"about_ca_topic_score_gemma":0.001961662,"domain_scores_codex":[0.9998931,0.0000179354,0.000007639291,0.00001667649,0.00002505568,0.00003968679],"domain_scores_gemma":[0.9998974,0.00002240313,0.00004368894,0.000008195837,0.00001403777,0.00001419983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001417792,0.00001838005,0.000299926,0.0000471456,0.00001014747,0.00004671955,0.00002078671,0.00005171634,0.9972315,0.00006099488,0.00002000623,0.002050897],"study_design_scores_gemma":[0.00006483426,0.001458281,0.01347922,0.000008837339,0.00003518959,0.000506061,0.00004203785,0.0005501277,0.9816459,0.00004556486,0.002157249,0.00000668015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940905,0.003008608,0.0009359455,0.00005386246,0.00001747933,0.00003543872,0.00011393,0.00002755476,0.001716731],"genre_scores_gemma":[0.9953027,0.002127363,0.001141941,0.00004852354,0.00001395273,0.00002771816,0.000171273,0.000007751929,0.001158776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001404201,"threshold_uncertainty_score":0.004697502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06939837007121354,"score_gpt":0.3882575302684993,"score_spread":0.3188591601972858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}