{"id":"W2086911420","doi":"10.1088/0031-9155/55/19/019","title":"A dynamic model for ALA-PDT of skin: simulation of temporal and spatial distributions of ground-state oxygen, photosensitizer and singlet oxygen","year":2010,"lang":"en","type":"article","venue":"Physics in Medicine and Biology","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre; McMaster University; McMaster University Medical Centre","funders":"University of Toronto","keywords":"Photosensitizer; Photobleaching; Photodynamic therapy; Singlet oxygen; Chemistry; Materials science; Fluence; Fluorescence; Photochemistry; Oxygen; Biophysics; Optics; Physics; Laser","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002789515,0.0001074825,0.0005038648,0.00007920216,0.00003380179,0.000001162748,0.00003137381,0.00006708605,0.000001736269],"category_scores_gemma":[0.0002003829,0.00007826467,0.00002572113,0.0001074172,0.001121441,0.00002536062,0.00004909281,0.0001358634,1.826019e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001096823,"about_ca_system_score_gemma":0.00004998621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000748395,"about_ca_topic_score_gemma":0.0004603186,"domain_scores_codex":[0.9992697,0.00002921111,0.0003031183,0.0001749118,0.00007542993,0.0001476915],"domain_scores_gemma":[0.9992018,0.0002951717,0.000139954,0.0001169395,0.0002001698,0.00004592046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0006721402,0.000139538,0.006286884,0.0003361067,0.0001109822,9.499636e-7,0.001562282,0.0001183124,0.9786059,0.0004861808,0.00001048942,0.01167029],"study_design_scores_gemma":[0.005214052,0.001604576,0.04399333,0.0001635627,0.0001026645,0.000009244642,0.0002820134,0.9131775,0.006681822,0.02859475,0.00005723239,0.0001192086],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794139,0.0002228139,0.01926388,0.0004180604,0.00003561166,0.0004142445,0.0002119264,0.000004141189,0.00001542662],"genre_scores_gemma":[0.9988593,0.0002549184,0.0006233539,0.00003969642,0.00003803406,0.00001135159,0.0001554162,0.000007458704,0.00001047542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.971924,"threshold_uncertainty_score":0.4131996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08928458091603783,"score_gpt":0.3982490689026724,"score_spread":0.3089644879866346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}