{"id":"W2086974999","doi":"10.1016/s1074-7613(01)00178-9","title":"WASP Recruitment to the T Cell:APC Contact Site Occurs Independently of Cdc42 Activation","year":2001,"lang":"en","type":"article","venue":"Immunity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":153,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"CDC42; Cell biology; Wiskott–Aldrich syndrome protein; Biology; PAK1; GTP'; Signaling proteins; Rac GTP-Binding Proteins; GTPase; T-cell receptor; RAC1; Signal transduction; T cell; Cell; Actin cytoskeleton; Cytoskeleton; Biochemistry; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002427737,0.0007287338,0.0006775861,0.0005667725,0.001063057,0.001101553,0.0004407243,0.0005806687,0.003767139],"category_scores_gemma":[0.000529505,0.0004811181,0.0005602706,0.0002932431,0.000396602,0.0008059864,0.001213498,0.001491182,0.002260664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008144074,"about_ca_system_score_gemma":0.0006937188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005923943,"about_ca_topic_score_gemma":0.001114935,"domain_scores_codex":[0.9994835,0.00004556511,0.00002604718,0.0001038837,0.0001115479,0.0002294887],"domain_scores_gemma":[0.9996727,0.00005365997,0.00003541536,0.0000479158,0.00007035868,0.0001200406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005620102,0.00003769848,0.0003162798,0.0001021533,0.00001081898,0.0005186554,0.00003519008,0.00007355558,0.9945858,0.00107171,0.0004273439,0.00225885],"study_design_scores_gemma":[0.00005434837,0.00008337545,0.007941825,0.00001236114,0.00001107532,0.0005558417,0.00007286812,0.001172177,0.9834474,0.0005102391,0.006127817,0.00001063681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.970611,0.003779925,0.01161814,0.0004708683,0.0004184941,0.0001642419,0.0009291904,0.0005488239,0.0114592],"genre_scores_gemma":[0.985699,0.0007622147,0.003142201,0.00008175371,0.00006667791,0.0001438465,0.001063709,0.00006357089,0.008977043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003767139,"threshold_uncertainty_score":0.01260233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03895963727609163,"score_gpt":0.2706101006899323,"score_spread":0.2316504634138407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}