{"id":"W2086974999","doi":"10.1016/s1074-7613(01)00178-9","title":"WASP Recruitment to the T Cell:APC Contact Site Occurs Independently of Cdc42 Activation","year":2001,"lang":"en","type":"article","venue":"Immunity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":153,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"CDC42; Cell biology; Wiskott–Aldrich syndrome protein; Biology; PAK1; GTP'; Signaling proteins; Rac GTP-Binding Proteins; GTPase; T-cell receptor; RAC1; Signal transduction; T cell; Cell; Actin cytoskeleton; Cytoskeleton; Biochemistry; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005094699,0.000225507,0.0003305927,0.0001319541,0.0003675075,0.00001564068,0.0005668337,0.0003020358,0.001036945],"category_scores_gemma":[0.00008202204,0.0001649144,0.0001282908,0.0002821667,0.0001444634,0.0001089997,0.0002591347,0.0006531645,0.001410031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008333392,"about_ca_system_score_gemma":0.00007243051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002735625,"about_ca_topic_score_gemma":0.0002687218,"domain_scores_codex":[0.9982512,0.0006029601,0.0004087085,0.0002459987,0.00006236354,0.0004287898],"domain_scores_gemma":[0.9985508,0.0002779126,0.0002322144,0.0007848283,0.0001276152,0.00002667087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004635414,0.0004135262,0.003616765,0.000009057154,0.0001311545,0.000002993445,0.001590125,0.00001328885,0.9815006,0.0001517045,0.00292306,0.00918413],"study_design_scores_gemma":[0.001317547,0.0004762407,0.01699459,0.00002690051,0.00004250372,0.00003540524,0.001018101,0.00000103281,0.7934938,0.00008775804,0.1863236,0.0001825244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991074,0.00101226,0.0001651678,0.0009048727,0.0008073587,0.0007227463,0.00003209074,0.00006148211,0.00522002],"genre_scores_gemma":[0.9924344,0.0001994766,0.00002708508,0.0004608409,0.00002821556,0.00006810948,0.0001549201,0.00001735927,0.006609626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1880068,"threshold_uncertainty_score":0.9998763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03895963727609163,"score_gpt":0.2706101006899323,"score_spread":0.2316504634138407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}