{"id":"W2087093349","doi":"10.1016/j.vaccine.2009.02.103","title":"Role of cell signaling in poxvirus-mediated foreign gene expression in mammalian cells","year":2009,"lang":"en","type":"article","venue":"Vaccine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases","keywords":"Biology; Transfection; PI3K/AKT/mTOR pathway; MAPK/ERK pathway; Signal transduction; Cell biology; Phosphoinositide 3-kinase; Gene expression; Kinase; Molecular biology; Virology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003970594,0.0005549436,0.0002994316,0.000291469,0.0004449613,0.001031295,0.0002531112,0.0006848988,0.001319393],"category_scores_gemma":[0.000171574,0.00017415,0.0003159904,0.0001547941,0.0003940244,0.0009740136,0.0002297302,0.0007252099,0.0004098036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000554928,"about_ca_system_score_gemma":0.0003150798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003811996,"about_ca_topic_score_gemma":0.0002839803,"domain_scores_codex":[0.9998388,0.00005700267,0.000009494621,0.0000235324,0.00002921522,0.00004192209],"domain_scores_gemma":[0.9999061,0.00004429403,0.00001350579,0.000008903559,0.00001244769,0.00001480728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002724814,0.00004096824,0.0001904876,0.00008815237,0.000008485202,0.0001662047,0.00005588421,0.0002189778,0.9898204,0.00586179,0.00007941513,0.003196765],"study_design_scores_gemma":[0.00002852165,0.0003155501,0.001524711,0.00001701964,0.00002211399,0.000264118,0.00009901547,0.002708677,0.9902965,0.001320417,0.003396314,0.000006982029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9411713,0.01517263,0.02987035,0.001064832,0.0001885563,0.0001356617,0.0003986311,0.0001643883,0.01183361],"genre_scores_gemma":[0.9897989,0.002948385,0.0037582,0.0001327993,0.00003193749,0.00005126122,0.0001622198,0.00001939255,0.00309682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001319393,"threshold_uncertainty_score":0.004413784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008875537720103672,"score_gpt":0.253009876566073,"score_spread":0.2441343388459693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}