{"id":"W2087146553","doi":"10.1006/gcen.2001.7701","title":"Molecular Evolution of Leptin","year":2001,"lang":"en","type":"article","venue":"General and Comparative Endocrinology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Leptin; Evolutionary biology; Computational biology; Genetics; Endocrinology; Obesity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006940634,0.0002905146,0.0003748549,0.0007722246,0.0007261843,0.001506126,0.0007818908,0.001026011,0.00178728],"category_scores_gemma":[0.0005902871,0.0003938282,0.0003155711,0.0004216394,0.001642782,0.001323245,0.0008482966,0.001730696,0.000468814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001795824,"about_ca_system_score_gemma":0.000550285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001687756,"about_ca_topic_score_gemma":0.001449541,"domain_scores_codex":[0.9996177,0.00005720204,0.00001551012,0.0001438003,0.00006815849,0.0000975698],"domain_scores_gemma":[0.9997159,0.00005204487,0.00004463702,0.0000402773,0.00008142736,0.0000657434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006508676,0.00009108443,0.009786278,0.0001901262,0.0001165833,0.001299283,0.001050396,0.003445146,0.6883938,0.1988359,0.001183165,0.09495734],"study_design_scores_gemma":[0.0001849924,0.0008497999,0.1747521,0.000443831,0.0002266257,0.007244701,0.00175835,0.01341979,0.316405,0.141893,0.3424866,0.0003352281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8944132,0.03684213,0.01733276,0.005750646,0.0003279735,0.00002716492,0.0002253199,0.0001400923,0.04494075],"genre_scores_gemma":[0.9776224,0.006053315,0.00411465,0.000550444,0.0001293732,0.00001463846,0.0001927048,0.00003555344,0.01128695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001795824,"threshold_uncertainty_score":0.01302969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05228638686170187,"score_gpt":0.2931913787064521,"score_spread":0.2409049918447502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}