{"id":"W2087146553","doi":"10.1006/gcen.2001.7701","title":"Molecular Evolution of Leptin","year":2001,"lang":"en","type":"article","venue":"General and Comparative Endocrinology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Leptin; Evolutionary biology; Computational biology; Genetics; Endocrinology; Obesity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00001611483,0.00006869951,0.0001372698,0.00005373928,0.00005756106,0.000005012098,0.00007058166,0.00002089571,0.0000563486],"category_scores_gemma":[0.00001042082,0.00005998081,0.00002661519,0.000107943,0.0001684772,0.0000504039,0.00004511672,0.00005002215,0.00002339471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001016556,"about_ca_system_score_gemma":0.00001025076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000291521,"about_ca_topic_score_gemma":0.000007452101,"domain_scores_codex":[0.9993927,0.0000875013,0.0001171084,0.0001808484,0.00006934214,0.0001525123],"domain_scores_gemma":[0.9997782,0.00002830795,0.00005095512,0.00008819981,0.0000241363,0.00003025797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002887887,0.00002830958,0.005071118,0.000001660979,0.000002538056,0.0000121741,0.00005475452,0.0003162432,0.7386584,0.2550472,0.00008378005,0.0006949766],"study_design_scores_gemma":[0.0003458665,0.0001352003,0.07044926,0.000002479046,0.000004082557,0.00009548855,0.00004200341,0.001350317,0.9099507,0.004923948,0.0126171,0.00008358138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843912,0.0002014829,0.001570798,0.0002702937,0.00006134963,0.0000647608,0.000001904347,0.00001922303,0.01341906],"genre_scores_gemma":[0.9988428,0.00006503018,0.0001876103,0.0001199398,0.0000318098,0.000004300677,9.548935e-7,0.000001769345,0.0007457495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2501232,"threshold_uncertainty_score":0.2445946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05228638686170187,"score_gpt":0.2931913787064521,"score_spread":0.2409049918447502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}