{"id":"W2087151025","doi":"10.1016/j.cellsig.2006.07.021","title":"Signalling complexes associated with adenylyl cyclase II are assembled during their biosynthesis","year":2006,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Adenylyl cyclase; Heterotrimeric G protein; G protein; Cell biology; Chemistry; Receptor; Gs alpha subunit; Signal transduction; GTPase; Agonist; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004266828,0.0004873814,0.0004626157,0.000123848,0.0007434827,0.0001336978,0.0003686908,0.0003215637,0.0001702768],"category_scores_gemma":[0.00005741048,0.000425051,0.0002551589,0.0002431642,0.00006024112,0.00001568936,0.000137904,0.0002445109,0.000009961752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005569921,"about_ca_system_score_gemma":0.00006414068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003815028,"about_ca_topic_score_gemma":0.00006719263,"domain_scores_codex":[0.9975407,0.0001527514,0.0004939822,0.0007703665,0.000349003,0.0006931785],"domain_scores_gemma":[0.9988657,0.0000659221,0.0003844971,0.0003403733,0.0001961371,0.0001473838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009388691,0.0001533444,0.0008128964,0.00003166701,0.0001720262,0.0000479793,0.00004700026,0.01011546,0.98833,0.00007089404,0.00004317848,0.00008168796],"study_design_scores_gemma":[0.0008088862,0.0001983001,0.0002893133,0.0002746157,0.00007634638,0.00001015981,0.0002323058,0.002044302,0.9947751,0.0001822775,0.0004801133,0.0006283217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.962823,0.001709319,0.03461109,0.00004281089,0.0001003283,0.0002764872,0.00002542523,0.0001037292,0.0003077902],"genre_scores_gemma":[0.9973131,0.00004686313,0.001043235,0.00005283824,0.0005543511,0.00003024707,0.0002762719,0.0001203812,0.0005627265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03449006,"threshold_uncertainty_score":0.9998201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009146177668617158,"score_gpt":0.1853111438821045,"score_spread":0.1761649662134873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}