{"id":"W2087225899","doi":"10.1016/j.aca.2012.01.050","title":"Mapping of sulfur metabolic pathway by LC Orbitrap mass spectrometry","year":2012,"lang":"en","type":"article","venue":"Analytica Chimica Acta","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada","funders":"National Natural Science Foundation of China; Natural Science Foundation of Shanghai","keywords":"Chemistry; Cysteine; Glutathione; Orbitrap; Methionine; Chromatography; Arsenite; Iodoacetic acid; Mass spectrometry; Biochemistry; Cystathionine beta synthase; Homocysteine; Sulfur; Yeast; Thiol; Amino acid; Arsenic; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003356319,0.0002565376,0.0004009674,0.0001542229,0.0000568383,0.00001400572,0.0004693302,0.0002525631,0.0001606116],"category_scores_gemma":[0.0001849819,0.000237194,0.00022082,0.0003520699,0.0001890481,0.000009366125,0.0001697313,0.0001836832,0.00002858851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001790629,"about_ca_system_score_gemma":0.00006004646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006262224,"about_ca_topic_score_gemma":0.000002138365,"domain_scores_codex":[0.998317,0.0001106021,0.0003953456,0.0003912496,0.0001731814,0.0006126052],"domain_scores_gemma":[0.998814,0.00005336922,0.0001863746,0.0006968965,0.00007057939,0.0001787855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002641194,0.0001299081,0.01218487,0.00001232504,0.0002744902,5.565173e-7,0.00004151131,6.273448e-8,0.981907,0.000493355,0.004827834,0.0001017545],"study_design_scores_gemma":[0.0003317739,0.0001072775,0.007433768,0.000006967971,0.00005118558,0.00002186261,0.00008778602,0.00001415004,0.8948836,0.0001781799,0.09659735,0.0002861178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882708,0.0007868534,0.0003022156,0.0003165086,0.0002549379,0.000123311,0.00006077853,0.00002268509,0.009861873],"genre_scores_gemma":[0.995357,0.0003947543,0.002631314,0.0003845016,0.0004486924,0.000008592705,0.0001934484,0.00003718027,0.000544458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09176952,"threshold_uncertainty_score":0.9672492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01322784333604845,"score_gpt":0.2444080199999547,"score_spread":0.2311801766639063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}