{"id":"W2087226517","doi":"10.2353/ajpath.2007.061043","title":"Neutrophil Elastase Converts Human Immature Dendritic Cells into Transforming Growth Factor-β1-Secreting Cells and Reduces Allostimulatory Ability","year":2007,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Agencia Nacional de Promoción Científica y Tecnológica; National Institutes of Health; National Institute of Dental and Craniofacial Research; Secretaría de Ciencia y Técnica, Universidad de Buenos Aires; Fundación Florencio Fiorini","keywords":"Elastase; Immunology; Neutrophil elastase; Biology; Cell biology; Dendritic cell; Transforming growth factor; Growth factor; Inflammation; Immune system; Receptor; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001473543,0.00033841,0.0002675856,0.0002521271,0.0001192257,0.0003966695,0.000199539,0.00026511,0.002059486],"category_scores_gemma":[0.0002044816,0.000150759,0.0003084671,0.0001519784,0.0001585471,0.0001502777,0.0001705328,0.0008870892,0.0006419494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001958294,"about_ca_system_score_gemma":0.0001727299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003304078,"about_ca_topic_score_gemma":0.000256442,"domain_scores_codex":[0.9997967,0.00002775506,0.00001976994,0.00002620991,0.00004182823,0.00008776094],"domain_scores_gemma":[0.9998141,0.00005130791,0.00002977945,0.00004430322,0.0000130373,0.00004755916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002898322,0.00009845556,0.0002158073,0.000009559961,0.000003799609,0.00008273484,0.00000720342,0.0000389803,0.997972,0.00006734183,0.00004367298,0.001170688],"study_design_scores_gemma":[0.0000426419,0.0003461389,0.002992366,0.000001857291,0.00001038289,0.0004310136,0.00001401896,0.0003443585,0.9949266,0.00004655039,0.0008416243,0.000002370829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974884,0.0005993725,0.0008290622,0.00005625654,0.00004509932,0.00001593567,0.0001856672,0.00005527091,0.0007250016],"genre_scores_gemma":[0.9962764,0.0005173616,0.0006406079,0.00004781727,0.00002380966,0.0000169426,0.0006584909,0.00001813022,0.001800481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002059486,"threshold_uncertainty_score":0.006889701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00556892603735479,"score_gpt":0.2413949902374775,"score_spread":0.2358260642001228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}