{"id":"W2087234818","doi":"10.1016/j.cell.2014.07.036","title":"The Atypical Cadherin Fat Directly Regulates Mitochondrial Function and Metabolic State","year":2014,"lang":"en","type":"article","venue":"Cell","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Mitochondrion; Cell biology; Oxidative phosphorylation; Hippo signaling pathway; Phosphorylation; Biochemistry; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008007067,0.0002289625,0.0001537096,0.00025997,0.0002676818,0.0004298698,0.0002358525,0.0002759376,0.001408495],"category_scores_gemma":[0.0001400531,0.0001556785,0.0001522993,0.0001884162,0.0003677382,0.0005412053,0.0003717636,0.0005343204,0.0002386652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004998159,"about_ca_system_score_gemma":0.0001898184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001056029,"about_ca_topic_score_gemma":0.002934325,"domain_scores_codex":[0.9999089,0.000009336485,0.000005098155,0.0000201341,0.00002065035,0.00003580341],"domain_scores_gemma":[0.9999082,0.00001218157,0.00002254853,0.00001169382,0.00001406794,0.0000312995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000135418,0.00001311836,0.001193843,0.00002745995,0.000006176565,0.0001206012,0.00001762378,0.0000490799,0.9959371,0.0008040817,0.00008251939,0.001612905],"study_design_scores_gemma":[0.00002607511,0.00009420784,0.03874774,0.000007481396,0.00003438926,0.0004799447,0.0001610814,0.002220424,0.9540192,0.000383308,0.003817503,0.000008731154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926765,0.001429821,0.002839336,0.0002324556,0.00003431232,0.000008435575,0.0002435726,0.00005868358,0.002476951],"genre_scores_gemma":[0.996989,0.000331529,0.0004512018,0.00004499355,0.000005886462,0.000005917864,0.0001463569,0.000009234168,0.002015877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001408495,"threshold_uncertainty_score":0.004711866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005384569437620203,"score_gpt":0.1973250697930125,"score_spread":0.1919405003553923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}