{"id":"W2087234818","doi":"10.1016/j.cell.2014.07.036","title":"The Atypical Cadherin Fat Directly Regulates Mitochondrial Function and Metabolic State","year":2014,"lang":"en","type":"article","venue":"Cell","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Mitochondrion; Cell biology; Oxidative phosphorylation; Hippo signaling pathway; Phosphorylation; Biochemistry; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118984,0.00009675605,0.00008531973,0.000009763472,0.0001424638,0.00003918282,0.00007859631,0.00007947148,0.000006327156],"category_scores_gemma":[0.00003536758,0.00006747844,0.00004481665,0.00003061163,0.00007257231,0.000001615905,0.00004246205,0.000065881,0.00002166915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002058026,"about_ca_system_score_gemma":0.00001213114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001156525,"about_ca_topic_score_gemma":0.00002249156,"domain_scores_codex":[0.9993606,0.00008543093,0.0001046415,0.0002141763,0.00006521327,0.000169923],"domain_scores_gemma":[0.9996347,0.0000251655,0.00003660003,0.0002099503,0.00002900697,0.00006461428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001410798,0.00001110493,0.0001109616,0.000004281898,0.00001316061,2.267167e-7,0.00002440817,0.00003143987,0.9952675,0.00004900217,0.0006210722,0.003725798],"study_design_scores_gemma":[0.0003103621,0.0001227602,0.0009536435,0.000002147389,0.00001438248,0.000001529022,0.00001034031,0.0001156255,0.6819885,0.0003608871,0.3160355,0.00008431798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945492,0.002206088,0.001849884,0.00007228932,0.0004123156,0.00007734072,0.000003867749,0.00001579294,0.000813178],"genre_scores_gemma":[0.9946804,0.000276944,0.0001620965,0.00008341138,0.0005317687,0.000009616594,0.00002161575,0.00001470857,0.004219437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3154145,"threshold_uncertainty_score":0.2751691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005384569437620203,"score_gpt":0.1973250697930125,"score_spread":0.1919405003553923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}