{"id":"W2087244516","doi":"10.1161/01.res.0000202051.28319.c8","title":"Inhibition of Versican Synthesis by Antisense Alters Smooth Muscle Cell Phenotype and Induces Elastic Fiber Formation In Vitro and in Neointima After Vessel Injury","year":2005,"lang":"en","type":"article","venue":"Circulation Research","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Heart, Lung, and Blood Institute; Marsden Fund; National Institutes of Health","keywords":"Versican; Elastin; Chemistry; Chondroitin sulfate proteoglycan; Tropoelastin; Neointima; Cell biology; Proteoglycan; Vascular smooth muscle; Chondroitin sulfate; Anatomy; Extracellular matrix; Biochemistry; Glycosaminoglycan; Endocrinology; Pathology; Internal medicine; Biology; Restenosis; Smooth muscle; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001098053,0.0003606046,0.0001506912,0.0001338746,0.0001290792,0.0002143869,0.0001239428,0.0001746822,0.0009005325],"category_scores_gemma":[0.00008598966,0.0001513744,0.0001803078,0.00008631294,0.000194031,0.0001192658,0.00009305457,0.0004323272,0.0002453435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002340747,"about_ca_system_score_gemma":0.0001807313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0010339,"about_ca_topic_score_gemma":0.001688221,"domain_scores_codex":[0.9998931,0.00001280224,0.00001258032,0.00002340529,0.00002603267,0.00003206113],"domain_scores_gemma":[0.9998759,0.00002463001,0.00003429588,0.00001393763,0.00001143718,0.00003973148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002982131,0.00001440595,0.00003979678,0.000007696261,0.000001326381,0.000009010671,0.000005621113,0.00002448213,0.9996766,0.00002322492,0.000006715079,0.000161478],"study_design_scores_gemma":[0.00001018712,0.0003586642,0.002703001,0.000002998271,0.00001128347,0.00005739549,0.00002171226,0.0007392027,0.9951994,0.00002014364,0.0008734583,0.000002475188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972292,0.0003575672,0.001228935,0.00004134043,0.00002440717,0.0000145392,0.0001637518,0.00003003193,0.0009102133],"genre_scores_gemma":[0.9931497,0.0007102564,0.001680824,0.00004169829,0.00001440293,0.00003450398,0.0004865635,0.00001785114,0.003864147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0010339,"threshold_uncertainty_score":0.003012598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01512814289712706,"score_gpt":0.2807372917310049,"score_spread":0.2656091488338779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}