{"id":"W2087325751","doi":"10.1096/fj.08-120998","title":"Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet‐induced weight loss","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; Canadian Heart Research Centre; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"MyoD; Allele; Biology; Skeletal muscle; Single-nucleotide polymorphism; Endocrinology; Genetics; Promoter; Gene; Internal medicine; Transcription factor; Gene expression; Molecular biology; Genotype; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002064284,0.0002198863,0.0001488771,0.0003882715,0.0001068847,0.000136179,0.000160882,0.0002597232,0.001389555],"category_scores_gemma":[0.0003328882,0.0001434294,0.0003957541,0.0002176089,0.000222093,0.00004009381,0.0001098345,0.0002708978,0.0003483914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001795081,"about_ca_system_score_gemma":0.0001301224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001020761,"about_ca_topic_score_gemma":0.001162278,"domain_scores_codex":[0.9998749,0.00002903215,0.0000160455,0.00003486301,0.00002884105,0.00001614576],"domain_scores_gemma":[0.9997488,0.00007599501,0.0000891138,0.00001935969,0.0000195737,0.00004712486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002772126,0.00005228429,0.004725339,0.00002508891,0.00002224175,0.0001811642,0.00002597307,0.0001145238,0.9928063,0.00007509225,0.00003093602,0.001663892],"study_design_scores_gemma":[0.0002243504,0.001036454,0.2524609,0.00004417957,0.0001665879,0.004094203,0.0001101174,0.006973351,0.7311778,0.0002974804,0.00338201,0.00003256146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967949,0.0002187143,0.002258005,0.00005736488,0.000009807893,0.00001613593,0.0003375417,0.00002753366,0.0002799379],"genre_scores_gemma":[0.9970784,0.00009174449,0.001620368,0.00004989912,0.000009019142,0.00002359301,0.000575117,0.00002388537,0.0005279999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001389555,"threshold_uncertainty_score":0.004648566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01598169774452509,"score_gpt":0.233128116719107,"score_spread":0.2171464189745819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}