{"id":"W2087413829","doi":"10.1126/science.1113579","title":"Stem Cell Depletion Through Epidermal Deletion of Rac1","year":2005,"lang":"en","type":"article","venue":"Science","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":246,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cell biology; Epidermis (zoology); RAC1; Stem cell; Biology; Regulator; Signal transduction; Anatomy; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000270776,0.00004565024,0.00008309332,0.00005579084,0.0000660354,0.00000594143,0.00008021844,0.00002390335,0.00006005366],"category_scores_gemma":[0.0000287794,0.00003807928,0.00002903625,0.0003556006,0.0002398633,0.000245943,0.00001813311,0.0000479404,0.00008286587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003102562,"about_ca_system_score_gemma":0.0001438361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002164002,"about_ca_topic_score_gemma":0.000007497937,"domain_scores_codex":[0.9992356,0.00001003939,0.0001300213,0.0001515059,0.0002962209,0.0001765761],"domain_scores_gemma":[0.9996486,0.00001532094,0.00004370958,0.0001435362,0.00007866183,0.0000702117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002067828,0.0006367657,0.08497821,0.0002716773,0.000006380353,0.00001155129,0.005075694,0.00063856,0.67027,0.005388975,0.002560081,0.2299553],"study_design_scores_gemma":[0.002595717,0.0005191919,0.1669595,0.000095618,0.00004256396,0.00005410378,0.001800709,0.006462547,0.7716695,0.000549755,0.0489843,0.0002664659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710588,0.0002984468,0.00510777,0.001180092,0.00007144775,0.0001117917,6.16858e-7,0.00002502499,0.02214601],"genre_scores_gemma":[0.9959997,0.00002411755,0.003043248,0.0006008199,0.00004629018,0.000002273079,0.000001229616,0.000003001715,0.0002793335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2296888,"threshold_uncertainty_score":0.1552828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0168384594428264,"score_gpt":0.2777009204645464,"score_spread":0.2608624610217199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}