{"id":"W2087517030","doi":"10.1371/journal.pone.0084182","title":"Epigenetic Reprogramming in Mist1−/− Mice Predicts the Molecular Response to Cerulein-Induced Pancreatitis","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Children’s Health Research Institute","funders":"Children's Health Foundation; Ministry of Education, India; Children's Health Research Institute; Sanofi; Canadian Institutes of Health Research; Lawson Health Research Institute; Eli Lilly and Company","keywords":"H3K4me3; Epigenetics; Reprogramming; Histone; Biology; Chromatin immunoprecipitation; Chromatin; Gene expression; Pancreatitis; Regulation of gene expression; Histone H4; Cell biology; Gene; Molecular biology; Genetics; Promoter; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002307081,0.0005246223,0.0004442559,0.0007504062,0.0001886585,0.0004880046,0.0002780768,0.0006108473,0.002591068],"category_scores_gemma":[0.0003244167,0.0004532315,0.0004826041,0.0002616105,0.0005654527,0.0003375216,0.0003532787,0.001108465,0.0005462306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003401217,"about_ca_system_score_gemma":0.0001441395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002969707,"about_ca_topic_score_gemma":0.0004995493,"domain_scores_codex":[0.9996866,0.00002888949,0.00004498898,0.0001273114,0.00005668518,0.00005541755],"domain_scores_gemma":[0.9993711,0.00006771194,0.0003172362,0.00004942086,0.00002858196,0.0001659641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003535139,0.00002232809,0.0009406737,0.00002915892,0.000007768414,0.0001253431,0.00001859943,0.000054598,0.9975562,0.0000549486,0.00003302771,0.0008038707],"study_design_scores_gemma":[0.00009624613,0.0008094924,0.1274314,0.00004331968,0.0001138567,0.002942229,0.000205699,0.00222385,0.8622547,0.0003616619,0.003480755,0.00003688483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945304,0.0005264001,0.002756117,0.000145021,0.00004033154,0.00002342238,0.001417324,0.0001609845,0.0004000255],"genre_scores_gemma":[0.9912742,0.0006460787,0.002683321,0.000149251,0.00002638278,0.0000940896,0.001530107,0.0001361999,0.003460447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002591068,"threshold_uncertainty_score":0.008668005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02107888714720087,"score_gpt":0.2379819560051639,"score_spread":0.2169030688579631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}