{"id":"W2087517236","doi":"10.1007/s00213-013-2993-0","title":"Abstinence from repeated amphetamine treatment induces depressive-like behaviors and oxidative damage in rat brain","year":2013,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University of Manitoba; University of British Columbia","funders":"Canadian Institutes of Health Research; Eli Lilly Canada; Manitoba Health Research Council; AstraZeneca Canada","keywords":"Amphetamine; Behavioural despair test; Psychology; Abstinence; Hippocampus; Open field; Dentate gyrus; Oxidative stress; Pharmacology; Internal medicine; Endocrinology; Medicine; Neuroscience; Psychiatry; Dopamine; Antidepressant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001413191,0.0004772353,0.0005281367,0.00046882,0.0003069344,0.0003350565,0.0002950345,0.000368283,0.001513823],"category_scores_gemma":[0.0001961215,0.0003579019,0.0004550506,0.000228562,0.0004939997,0.0003414711,0.0003352757,0.001247701,0.0003169934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003938528,"about_ca_system_score_gemma":0.0004778776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001751583,"about_ca_topic_score_gemma":0.007470024,"domain_scores_codex":[0.9998565,0.00001500784,0.00001326639,0.00002735241,0.00003578341,0.000052135],"domain_scores_gemma":[0.999712,0.00003500127,0.00007328529,0.00005835006,0.00002578559,0.00009550896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003278769,0.0003587399,0.002498854,0.00002740539,0.00004807934,0.0001535458,0.00005184743,0.00002358033,0.9906877,0.00007807367,0.00005758154,0.002735847],"study_design_scores_gemma":[0.0001418424,0.004267474,0.1112424,0.00001749882,0.0001220559,0.0007360858,0.0001776731,0.0007999021,0.8816805,0.000225441,0.0005642493,0.00002485623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990007,0.0002078002,0.0002813537,0.00004412337,0.00001652671,0.00001026011,0.0001453415,0.00001917086,0.0002746472],"genre_scores_gemma":[0.9960645,0.00040778,0.0006246166,0.00006075611,0.0000184577,0.00004076075,0.0006427009,0.00001678606,0.002123673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001751583,"threshold_uncertainty_score":0.005064189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03152753298478435,"score_gpt":0.3295016407009889,"score_spread":0.2979741077162046,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}