{"id":"W2087574858","doi":"10.1074/jbc.m004882200","title":"An Alternative, Human SRC Promoter and Its Regulation by Hepatic Nuclear Factor-1α","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Promoter; Biology; Molecular biology; Proto-oncogene tyrosine-protein kinase Src; Exon; Transcription factor; Gene isoform; Gene; Alternative splicing; Gene expression; Genetics; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002333511,0.0003049791,0.0001866106,0.0002566174,0.0001610982,0.0003273941,0.0002036515,0.0001770614,0.001045945],"category_scores_gemma":[0.0002898935,0.0002120652,0.0002837619,0.0001651122,0.0003226517,0.0001524297,0.0003076697,0.0005896243,0.0005808774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004146514,"about_ca_system_score_gemma":0.0004190045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006335715,"about_ca_topic_score_gemma":0.001016573,"domain_scores_codex":[0.9996661,0.00003724175,0.00002002979,0.0001221783,0.0001044999,0.00004995382],"domain_scores_gemma":[0.9998355,0.00002671755,0.00004270087,0.00002043832,0.00004023505,0.00003431314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001499385,0.00003004036,0.0004491764,0.00003254537,0.000002876446,0.00008922268,0.00007522071,0.00004778721,0.9951746,0.0005348618,0.00005181848,0.003361978],"study_design_scores_gemma":[0.00007284099,0.0003307967,0.01129781,0.00003537927,0.00001946442,0.00194131,0.0001336418,0.002353193,0.9704926,0.0004427083,0.01286734,0.0000128163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9533129,0.003714369,0.03874559,0.0001978902,0.000151227,0.00009864288,0.0005749601,0.0001437233,0.003060739],"genre_scores_gemma":[0.9642558,0.001677537,0.02082242,0.0001064602,0.00005683734,0.0001228741,0.003388922,0.00004685274,0.009522282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001045945,"threshold_uncertainty_score":0.003499031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02629600863615127,"score_gpt":0.2756431146235727,"score_spread":0.2493471059874214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}