{"id":"W2087580629","doi":"10.1007/s11912-001-0052-1","title":"The biology of acute promyelocytic leukemia","year":2001,"lang":"en","type":"review","venue":"Current Oncology Reports","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Acute promyelocytic leukemia; Medicine; Retinoic acid; Cancer research; Promyelocytic leukemia protein; Retinoid; Leukemia; Fusion protein; Differentiation therapy; Tretinoin; Carcinogenesis; Transcription factor; Retinoic acid receptor alpha; Retinoic acid receptor; Internal medicine; Biology; Biochemistry; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000798857,0.001017653,0.00156088,0.00228549,0.0004791933,0.001667035,0.001338931,0.001265278,0.001842881],"category_scores_gemma":[0.0004873347,0.0003503947,0.000330228,0.002605223,0.001318713,0.001974605,0.0008164397,0.002046355,0.002476553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001260698,"about_ca_system_score_gemma":0.001188019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001312538,"about_ca_topic_score_gemma":0.001784715,"domain_scores_codex":[0.9997841,0.0000380545,0.00003394859,0.00003635752,0.00008380309,0.00002384835],"domain_scores_gemma":[0.9997732,0.00007974413,0.00003277724,0.00001323125,0.00006768126,0.00003339807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001722967,0.00005712296,0.0002966794,0.007551048,0.00004986523,0.000751311,0.0001201078,0.0005206038,0.01029586,0.008503448,0.03981609,0.9318656],"study_design_scores_gemma":[0.00001677347,0.00003856542,0.0003066783,0.0006303009,0.00003905781,0.001472282,0.0000601721,0.00003542257,0.001129433,0.002176353,0.9940858,0.000009147536],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001321554,0.9975083,0.0002101801,0.0004147169,0.0004724617,0.000004654165,0.000008658252,0.000008123294,0.001240735],"genre_scores_gemma":[0.0006269773,0.997832,0.0001606847,0.0001981908,0.0003810863,0.000004620404,0.00001675924,8.409856e-7,0.0007788276],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00228549,"threshold_uncertainty_score":0.009147048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04780793328525591,"score_gpt":0.3966410529010649,"score_spread":0.348833119615809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}