{"id":"W2087637929","doi":"10.1371/journal.pone.0118150","title":"Development and Validation of an Internationally-Standardized, High-Resolution Capillary Gel-Based Electrophoresis PCR-Ribotyping Protocol for Clostridium difficile","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"Centers for Disease Control and Prevention; Universiteit Leiden; European Centre for Disease Prevention and Control; Public Health Agency; Public Health Agency of Canada","keywords":"Ribotyping; Typing; Biology; Clostridium difficile; Capillary electrophoresis; Computational biology; Polymerase chain reaction; Microbiology; Genetics; Molecular biology; Antibiotics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006090858,0.000220715,0.0004592204,0.0002871131,0.0001160735,0.00004160845,0.0001293351,0.0001442017,0.00005221706],"category_scores_gemma":[0.0005261487,0.0002088668,0.00006598356,0.0002487646,0.00008517219,0.0001090695,0.00006406259,0.0001855689,0.000006674257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005183622,"about_ca_system_score_gemma":0.001049648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006196419,"about_ca_topic_score_gemma":0.00001829696,"domain_scores_codex":[0.9975216,0.00007417417,0.0005500092,0.0004083919,0.001069247,0.0003765594],"domain_scores_gemma":[0.9980392,0.000109225,0.0001902019,0.0002993915,0.001060502,0.0003014686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01088702,0.004933503,0.0009958411,0.001554025,0.0004903984,0.0000158028,0.0003283314,0.0001066812,0.9765486,0.0003273173,0.0007140596,0.003098498],"study_design_scores_gemma":[0.007677943,0.001441763,0.0003658179,0.0004424133,0.0001422623,0.000004941026,0.00008505962,0.003890972,0.983969,0.00006901888,0.001702918,0.0002079389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961347,0.00004937711,0.001081441,0.0005042845,0.00002102987,0.03670479,0.00005767831,0.0000698415,0.0001645354],"genre_scores_gemma":[0.900154,0.00001211121,0.04370519,0.00007379712,0.0003706115,0.05470026,0.0006834941,0.00007615665,0.0002243971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06119304,"threshold_uncertainty_score":0.8517342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09176386284644954,"score_gpt":0.3195491564888871,"score_spread":0.2277852936424375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}