{"id":"W2087637929","doi":"10.1371/journal.pone.0118150","title":"Development and Validation of an Internationally-Standardized, High-Resolution Capillary Gel-Based Electrophoresis PCR-Ribotyping Protocol for Clostridium difficile","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"Centers for Disease Control and Prevention; Universiteit Leiden; European Centre for Disease Prevention and Control; Public Health Agency; Public Health Agency of Canada","keywords":"Ribotyping; Typing; Biology; Clostridium difficile; Capillary electrophoresis; Computational biology; Polymerase chain reaction; Microbiology; Genetics; Molecular biology; Antibiotics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0298164,0.001703357,0.001858027,0.003229832,0.001572454,0.002472667,0.003622622,0.002545281,0.001716483],"category_scores_gemma":[0.03054307,0.001046965,0.001878156,0.00261225,0.001658367,0.00145599,0.00277299,0.002699558,0.002655851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001190413,"about_ca_system_score_gemma":0.003715971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00240944,"about_ca_topic_score_gemma":0.00383175,"domain_scores_codex":[0.9652655,0.01200669,0.005402679,0.005542038,0.01012249,0.001660613],"domain_scores_gemma":[0.9683645,0.005131779,0.003058509,0.007451251,0.01524245,0.0007514767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006850173,0.0007623163,0.007998047,0.0009880086,0.0001684461,0.0003603096,0.001481317,0.003911684,0.9012757,0.002058013,0.001508353,0.07880273],"study_design_scores_gemma":[0.0002229232,0.004244318,0.0318792,0.0005048288,0.0005413365,0.001388998,0.0008403693,0.01524329,0.9112033,0.001359978,0.03231642,0.000255039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1106038,0.001173954,0.8705732,0.0003083154,0.0003080151,0.01044405,0.001796369,0.001174705,0.003617706],"genre_scores_gemma":[0.08086344,0.0008831267,0.9003308,0.0002990434,0.00004855442,0.008209182,0.006900544,0.0003944362,0.002070832],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.0298164,"threshold_uncertainty_score":0.1576861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09176386284644954,"score_gpt":0.3195491564888871,"score_spread":0.2277852936424375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}