{"id":"W2087698610","doi":"10.1007/s00726-012-1450-4","title":"4-[18F]Fluoro-N-methyl-N-(propyl-2-yn-1-yl)benzenesulfonamide ([18F]F-SA): a versatile building block for labeling of peptides, proteins and oligonucleotides with fluorine-18 via Cu(I)-mediated click chemistry","year":2013,"lang":"en","type":"article","venue":"Amino Acids","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Bioconjugation; Chemistry; Click chemistry; Oligonucleotide; Combinatorial chemistry; Radiosynthesis; Sulfonamide; Lipophilicity; Stereochemistry; Biochemistry; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002203938,0.0006062887,0.000681372,0.0000597964,0.0003168707,0.0001132399,0.0005475752,0.0002945474,0.0005686738],"category_scores_gemma":[0.0003098021,0.0005831294,0.0001731303,0.0003801869,0.0003746166,0.0002907323,0.0002386469,0.0004431647,0.00002518895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001308122,"about_ca_system_score_gemma":0.0001375975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003335559,"about_ca_topic_score_gemma":0.00001808087,"domain_scores_codex":[0.9970195,0.00001720704,0.0008437122,0.0009352536,0.000410154,0.0007741582],"domain_scores_gemma":[0.9972708,0.0004955619,0.0005125755,0.0009521708,0.0004137427,0.0003552126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009408796,0.0002200908,0.003600477,0.00129743,0.0001706264,0.000005692014,0.0001587292,0.00006074369,0.9912071,0.00005210199,0.0004322769,0.002700675],"study_design_scores_gemma":[0.00196701,0.0000841099,0.0004425709,0.0003607026,0.0001660783,0.00006417831,0.0004647317,0.002192735,0.9889697,0.0002372447,0.004367866,0.0006830713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939405,0.0003583581,0.0002823573,0.0002105533,0.00002780077,0.0007889722,0.0002503707,0.0002663196,0.003874711],"genre_scores_gemma":[0.9773123,0.00008134574,0.01790796,0.00006194951,0.0003336068,0.001116638,0.000280227,0.0001251889,0.002780833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0176256,"threshold_uncertainty_score":0.999662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01123583679638706,"score_gpt":0.2348039305525098,"score_spread":0.2235680937561227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}