{"id":"W2087713453","doi":"10.1128/jvi.01115-12","title":"Sheeppox Virus SPPV14 Encodes a Bcl-2-Like Cell Death Inhibitor That Counters a Distinct Set of Mammalian Proapoptotic Proteins","year":2012,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Biology; Myxoma virus; Virus; Programmed cell death; Virology; Apoptosis; Vaccinia; Puma; Virulence; Poxviridae; Oncolytic virus; Cell biology; Genetics; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001012611,0.0002385661,0.000411311,0.0001658907,0.00006455944,0.00001652574,0.0004311354,0.0002591487,0.0001210768],"category_scores_gemma":[0.00007477201,0.0001937319,0.0002357163,0.0000974194,0.0002138258,0.0000191619,0.0001324363,0.0003383858,0.00001715107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005121308,"about_ca_system_score_gemma":0.0002333098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002444377,"about_ca_topic_score_gemma":0.00009878017,"domain_scores_codex":[0.9979463,0.0003565239,0.0005298656,0.0002193166,0.0003733237,0.000574642],"domain_scores_gemma":[0.9987025,0.00003336081,0.000468033,0.0003617959,0.0001751421,0.0002591485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004363838,0.0003608803,0.01779781,0.00007190071,0.0001343266,0.00002106222,0.0002296782,0.00005483704,0.9756467,0.000006283768,0.0005849851,0.0007277179],"study_design_scores_gemma":[0.001711894,0.009255959,0.006170396,0.00002821963,0.00006949659,0.0002554234,0.0001125983,0.00002162309,0.9743372,0.00004570283,0.007767983,0.0002234611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965296,0.001804628,0.0005336842,0.0002419376,0.0003250967,0.0003234137,0.00004176612,0.000004487958,0.0001953236],"genre_scores_gemma":[0.9976829,0.0002313342,0.0007631638,0.0002525399,0.00074793,0.000018541,0.00001718743,0.00004181956,0.0002446356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01162741,"threshold_uncertainty_score":0.7900157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0261522364274991,"score_gpt":0.2924831022621967,"score_spread":0.2663308658346976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}