{"id":"W2087733469","doi":"10.1182/blood-2004-04-1653","title":"Molecular interactions involved in HOXB4-induced activation of HSC self-renewal","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"National Heart, Lung, and Blood Institute","keywords":"Haematopoiesis; Biology; In vivo; Stem cell; In vitro; Cancer research; Bone marrow; Leukemia; Transplantation; Cell biology; Molecular biology; Immunology; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006049871,0.00007760296,0.00007729594,0.00005741011,0.00002184327,0.00000313233,0.00006394598,0.0001079918,0.000004001366],"category_scores_gemma":[0.00002341432,0.00008045008,0.00003744588,0.0001000479,0.00001712704,0.000004526086,0.00003499371,0.00004864669,0.000003444271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001508164,"about_ca_system_score_gemma":0.0000748387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003238195,"about_ca_topic_score_gemma":0.0001059233,"domain_scores_codex":[0.9995066,0.00002665917,0.0001526141,0.0001644191,0.0000498604,0.00009986472],"domain_scores_gemma":[0.9997556,0.000003667864,0.00006140487,0.0001229443,0.00003350397,0.00002293593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002444348,0.0002813741,0.008945787,0.000007354324,0.00004512034,0.000001281515,0.0000607815,0.0001104169,0.9900029,0.0001150789,0.000003105903,0.0004023219],"study_design_scores_gemma":[0.001188834,0.0001065094,0.0225423,0.00001452329,0.00001210578,0.000004798667,0.00004014208,0.000002183296,0.9755006,0.0003732289,0.0001278797,0.00008684272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989409,0.00005933997,0.000199932,0.00009548645,0.00006003342,0.0001062859,0.000001825485,0.000009123162,0.0005270272],"genre_scores_gemma":[0.9985652,0.00001595999,0.001161297,0.00006076756,0.00003093818,0.00001405012,0.0001286878,0.000006958239,0.00001616863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01450228,"threshold_uncertainty_score":0.3280659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007791241079497072,"score_gpt":0.2376182624954039,"score_spread":0.2298270214159068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}