{"id":"W2087746152","doi":"10.1101/gad.1708608","title":"RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability","year":2008,"lang":"en","type":"article","venue":"Genes & Development","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":213,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Bloom syndrome; Biology; Homologous recombination; Genome instability; Point mutation; Genetics; DNA; Cell biology; Sister chromatid exchange; RecQ helicase; Molecular biology; Helicase; Mutation; DNA damage; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001888126,0.0009247375,0.0003710859,0.0003540019,0.0003079118,0.0005234758,0.0003592085,0.0003828959,0.0009595727],"category_scores_gemma":[0.0001923802,0.0002656284,0.0002676668,0.0001916064,0.0002472397,0.0002825177,0.0004879869,0.0004861511,0.0007669291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005700598,"about_ca_system_score_gemma":0.0003103071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003615048,"about_ca_topic_score_gemma":0.0005482767,"domain_scores_codex":[0.9998392,0.00001905602,0.00001746414,0.00004921574,0.00005064131,0.00002430276],"domain_scores_gemma":[0.9998226,0.00001344481,0.00005392017,0.0000260212,0.0000177357,0.000066318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007843922,0.00001385626,0.0005966479,0.00004038807,0.000007474419,0.0001198965,0.00001012377,0.00005702342,0.9965609,0.0002241537,0.000141966,0.002149075],"study_design_scores_gemma":[0.00003271958,0.0001504318,0.01151096,0.000009467024,0.00003133426,0.002629179,0.00002538288,0.001784672,0.9655813,0.0001399316,0.01809303,0.00001162888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.953375,0.01200248,0.02614161,0.0004815947,0.0001749059,0.0001243476,0.001497387,0.001544466,0.004658109],"genre_scores_gemma":[0.963631,0.001593235,0.02391848,0.0001250612,0.00003960885,0.00006209024,0.003442437,0.0001508427,0.007037301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009595727,"threshold_uncertainty_score":0.004136086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02769393686680093,"score_gpt":0.2438380192229327,"score_spread":0.2161440823561318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}